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[心房颤动与心力衰竭]

[Atrial fibrillation and heart failure].

作者信息

Bergau Leonard

机构信息

Abteilung für Kardiologie und Pneumologie, Universitätsmedizin Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Deutschland.

出版信息

Inn Med (Heidelb). 2024 Aug;65(8):755-761. doi: 10.1007/s00108-024-01743-x. Epub 2024 Jul 15.

DOI:10.1007/s00108-024-01743-x
PMID:39007960
Abstract

Atrial fibrillation and heart failure are among the most common cardiovascular diseases and have a significant impact on the mortality and morbidity of affected patients. From a pathophysiological perspective, the two diseases are closely related and often perpetuate each other. Therefore, effective management of atrial fibrillation is now a central component of modern heart failure treatment. Based on current data, sinus rhythm should primarily be permanently maintained in patients with systolic heart failure. Catheter ablation has recently proven to be advantageous over purely pharmacological therapy and is therefore the treatment of choice for many patients with heart failure and atrial fibrillation. In patients with diastolic heart failure (heart failure with preserved ejection fraction [HFpEF]), the effect of catheter ablation is less clear. Data from randomized studies are urgently needed in order to further assess efficacy in this population.

摘要

心房颤动和心力衰竭是最常见的心血管疾病,对受影响患者的死亡率和发病率有重大影响。从病理生理学角度来看,这两种疾病密切相关且常常相互影响。因此,有效管理心房颤动现在是现代心力衰竭治疗的核心组成部分。根据目前的数据,收缩性心力衰竭患者应主要永久维持窦性心律。最近已证明导管消融比单纯药物治疗更具优势,因此是许多心力衰竭合并心房颤动患者的首选治疗方法。对于舒张性心力衰竭(射血分数保留的心力衰竭[HFpEF])患者,导管消融的效果尚不清楚。迫切需要随机研究的数据,以便进一步评估该人群中的疗效。

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1
[Atrial fibrillation and heart failure].[心房颤动与心力衰竭]
Inn Med (Heidelb). 2024 Aug;65(8):755-761. doi: 10.1007/s00108-024-01743-x. Epub 2024 Jul 15.
2
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本文引用的文献

1
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AV junction ablation and cardiac resynchronization for patients with permanent atrial fibrillation and narrow QRS: the APAF-CRT mortality trial.
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7
Ablation Versus Drug Therapy for Atrial Fibrillation in Heart Failure: Results From the CABANA Trial.心房颤动心力衰竭中消融与药物治疗的比较:CABANA 试验结果。
Circulation. 2021 Apr 6;143(14):1377-1390. doi: 10.1161/CIRCULATIONAHA.120.050991. Epub 2021 Feb 8.
8
Heart failure drug treatment: the fantastic four.心力衰竭药物治疗:神奇的四种药物。
Eur Heart J. 2021 Feb 11;42(6):681-683. doi: 10.1093/eurheartj/ehaa1012.
9
Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation.冷冻消融或药物治疗用于初始治疗心房颤动。
N Engl J Med. 2021 Jan 28;384(4):305-315. doi: 10.1056/NEJMoa2029980. Epub 2020 Nov 16.
10
Cryoballoon Ablation as Initial Therapy for Atrial Fibrillation.冷冻球囊消融术作为心房颤动的初始治疗。
N Engl J Med. 2021 Jan 28;384(4):316-324. doi: 10.1056/NEJMoa2029554. Epub 2020 Nov 16.