Naidoo L, Jailal I, Moodley J, Desai R
Obstet Gynecol. 1985 Oct;66(4):500-2.
Carbohydrate metabolism was evaluated in 20 twin gestations and 20 singleton pregnancies. The groups were matched for age, parity, weight, height, and gestational age. Intravenous glucose tolerance tests were performed on all women in the third trimester of pregnancy using a glucose load of 0.5 g/kg body weight. Venous plasma glucose and insulin level were measured and statistically compared. The glucose disappearance rates (K) were not different in the two groups. No significant differences in the mean insulin or glucose responses were found between singleton and twin pregnancies. Thus, twin gestations are not at higher metabolic risk of gestational diabetes than are singleton pregnancies.
对20例双胎妊娠和20例单胎妊娠进行了碳水化合物代谢评估。两组在年龄、产次、体重、身高和孕周方面进行了匹配。在妊娠晚期对所有女性进行静脉葡萄糖耐量试验，葡萄糖负荷为0.5 g/kg体重。测量静脉血浆葡萄糖和胰岛素水平并进行统计学比较。两组的葡萄糖消失率（K）没有差异。单胎妊娠和双胎妊娠之间在平均胰岛素或葡萄糖反应方面未发现显著差异。因此，双胎妊娠患妊娠期糖尿病的代谢风险并不高于单胎妊娠。
