School of Medicine, University of California San Diego, La Jolla, CA, USA
K.N. Domingo and K.L. Gabaldon contributed equally.
Eur Respir Rev. 2024 Jun 12;33(172). doi: 10.1183/16000617.0249-2023. Print 2024 Apr.
Paediatric populations are particularly vulnerable to respiratory diseases caused and exacerbated by aeroallergens, pollutants and infectious agents. Worsening climate change is expected to increase the prevalence of pollutants and aeroallergens while amplifying disease severity and causing disproportionate effects in under-resourced areas. The purpose of this narrative review is to summarise the role of anthropogenic climate change in the literature examining the future impact of aeroallergens, pollutants and infectious agents on paediatric respiratory diseases with a focus on equitable disease mitigation. The aeroallergens selected for discussion include pollen, dust mites and mould as these are prevalent triggers of paediatric asthma worldwide. Human rhinovirus and respiratory syncytial virus are key viruses interacting with climate change and pollution and are primary causal agents of viral respiratory disease. Within this review, we present the propensity for aeroallergens, climate change and pollution to synergistically exacerbate paediatric respiratory disease and outline measures that can ameliorate the expected increase in morbidity and severity of disease through a health equity lens. We support shifting from fossil fuels to renewable energy worldwide, across sectors, as a primary means of reducing increases in morbidity.
儿科人群特别容易受到过敏原、污染物和传染病引起和加重的呼吸道疾病的影响。预计气候变化的恶化将增加污染物和过敏原的流行,同时放大疾病的严重程度,并在资源匮乏地区造成不成比例的影响。本叙述性综述的目的是总结人为气候变化在文献中对过敏原、污染物和传染病对儿科呼吸道疾病未来影响的作用,重点是公平缓解疾病。选择讨论的过敏原包括花粉、尘螨和霉菌,因为这些是全球儿童哮喘的常见触发因素。人类鼻病毒和呼吸道合胞病毒是与气候变化和污染相互作用的关键病毒,也是病毒性呼吸道疾病的主要病原体。在本综述中,我们提出了过敏原、气候变化和污染协同加重儿科呼吸道疾病的倾向,并概述了通过公平健康视角可以减轻预期发病率和疾病严重程度增加的措施。我们支持在全球范围内,跨越各个部门,从化石燃料转向可再生能源,以此作为减少发病率增加的主要手段。