Khilnani Neil M, Xia Jimmy J, Winokur Ronald S, Meissner Mark H
Division of Interventional Radiology, Weill Cornell Medicine-NewYork Presbyterian Hospital, 525 East 68th Street, New York, NY, 10065, USA.
Department of Surgery, University of Washington, 1959 NE Pacific Street, Seattle, WA, 98195, USA.
Cardiovasc Intervent Radiol. 2024 Dec;47(12):1650-1668. doi: 10.1007/s00270-024-03782-1. Epub 2024 Jul 15.
Pelvic venous reflux and obstruction can lead to chronic pelvic pain and extra-pelvic varicosities. This paper will discuss the contemporary understanding of this pathophysiology and its clinical manifestations. It will review evidence-based clinical and imaging criteria of pelvic venous disorders, data supporting benefit from venous interventions, criticisms of the available data and highlight evidence research gaps that exist. Finally, it will argue that comparative outcomes research utilizing standardized patient selection for embolization and stenting, embolization treatment strategies that eliminate the pelvic varices (at least to start), and clinically relevant outcome measures are necessary to establish the benefit of vascular treatments.
盆腔静脉反流和梗阻可导致慢性盆腔疼痛和盆腔外静脉曲张。本文将探讨对这种病理生理学及其临床表现的当代认识。它将回顾盆腔静脉疾病基于证据的临床和影像学标准、支持静脉干预益处的数据、对现有数据的批评,并突出存在的证据研究空白。最后,本文将论证,利用标准化患者选择进行栓塞和支架置入的比较结果研究、消除盆腔静脉曲张的栓塞治疗策略(至少开始时)以及临床相关的结果测量对于确定血管治疗的益处是必要的。