Medicines Optimisation Older People Pharmacy Team, Belfast Health and Social Care Trust, Belfast, UK.
School of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
BMC Geriatr. 2024 Jul 15;24(1):604. doi: 10.1186/s12877-024-05189-6.
The World Falls guidance includes medication review as part of its recommended multifactorial risk assessment for those at high risk of falling. Use of Falls Risk Increasing Drugs (FRIDs) along with polypharmacy and anticholinergic burden (ACB) are known to increase the risk of falls in older people.
The impact of a community falls pharmacist within a hospital Trust, working as part of a multi-professional community falls prevention service, was evaluated in 92 people aged 65 years or older, by analysing data before and after pharmacist review, namely: number and type of FRIDs prescribed; anticholinergic burden score using ACBcalc; appropriateness of medicines prescribed; bone health review using an approved too; significance of clinical intervention; cost avoidance, drug cost savings and environmental impact.
Following pharmacist review, there was a reduction in polypharmacy (mean number of medicines prescribed per patient reduced by 8%; p < 0.05) and anticholinergic burden score (average score per patient reduced by 33%; p < 0.05). Medicines appropriateness improved (Medicines Appropriateness Index score decreased by 56%; p < 0.05). There were 317 clinically significant interventions by the community falls pharmacist. One hundred and one FRIDs were deprescribed. Annual cost avoidance and drug cost savings were £40,689-£82,642 and avoidable carbon dioxide (CO) emissions from reducing inappropriate prescribing amounted to 941 kg CO.
The community falls pharmacist role increases prescribing appropriateness in the older population at risk of falls, and is an effective and cost-efficient means to optimise medicines in this population, as well as having a positive impact on the environment.
《世界跌倒指南》将药物审查作为其针对高跌倒风险人群的多因素风险评估的一部分。已知使用跌倒风险增加药物(FRIDs)、联合用药和抗胆碱能负担(ACB)会增加老年人跌倒的风险。
评估了一家医院信托内的社区跌倒药剂师在多专业社区跌倒预防服务中的作用,该药剂师通过分析药剂师审查前后的数据分析了 92 名 65 岁或以上的患者的数据,具体包括:处方的 FRIDs 数量和类型;使用 ACBcalc 计算的抗胆碱能负担评分;处方药物的适宜性;使用批准的工具进行骨骼健康评估;临床干预的重要性;成本避免、药物成本节约和环境影响。
审查后,联合用药(每位患者处方的药物数量减少 8%;p<0.05)和抗胆碱能负担评分(每位患者的平均评分减少 33%;p<0.05)均有所减少。药物适宜性提高(药物适宜性指数评分降低 56%;p<0.05)。社区跌倒药剂师进行了 317 次具有临床意义的干预。共停用 101 种 FRIDs。每年可避免的费用和药物成本节约为 40689-82642 英镑,减少不适当处方可避免的二氧化碳(CO)排放量为 941 公斤 CO。
社区跌倒药剂师的角色增加了处于跌倒风险中的老年人群的处方适宜性,是优化该人群药物治疗的有效且具有成本效益的方法,同时对环境也有积极影响。