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Hydrogen sulfide derived from apoptotic cells supports immune homeostasis.

作者信息

Xu Ying, Chen Suzhen, Liu Junli

机构信息

Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

出版信息

Metabol Open. 2024 Feb 21;22:100276. doi: 10.1016/j.metop.2024.100276. eCollection 2024 Jun.

DOI:10.1016/j.metop.2024.100276
PMID:39011162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11247202/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/138d/11247202/b32b7354482a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/138d/11247202/b32b7354482a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/138d/11247202/b32b7354482a/gr1.jpg

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Hydrogen sulfide derived from apoptotic cells supports immune homeostasis.凋亡细胞产生的硫化氢有助于维持免疫稳态。
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2
HS serves as the immunoregulatory essence of apoptotic cell death.HS 作为凋亡细胞死亡的免疫调节本质。
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本文引用的文献

1
Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation.细胞凋亡释放硫化氢抑制 Th17 细胞分化。
Cell Metab. 2024 Jan 2;36(1):78-89.e5. doi: 10.1016/j.cmet.2023.11.012. Epub 2023 Dec 18.
2
Mesenchymal Stem Cell-Derived Apoptotic Bodies: Biological Functions and Therapeutic Potential.间充质干细胞来源的凋亡小体：生物学功能与治疗潜能。
Cells. 2022 Dec 1;11(23):3879. doi: 10.3390/cells11233879.
3
Apoptotic vesicles inherit SOX2 from pluripotent stem cells to accelerate wound healing by energizing mesenchymal stem cells.
凋亡小体从多能干细胞中继承 SOX2，通过为间充质干细胞供能来加速伤口愈合。
Acta Biomater. 2022 Sep 1;149:258-272. doi: 10.1016/j.actbio.2022.07.009. Epub 2022 Jul 10.
4
Hydrogen sulfide and metal interaction: the pathophysiological implications.硫化氢与金属相互作用：病理生理学意义。
Mol Cell Biochem. 2022 Sep;477(9):2235-2248. doi: 10.1007/s11010-022-04443-y. Epub 2022 Apr 24.
5
The role of hydrogen sulphide signalling in macrophage activation.硫化氢信号在巨噬细胞激活中的作用。
Immunology. 2021 Jan;162(1):3-10. doi: 10.1111/imm.13253. Epub 2020 Oct 6.
6
Hydrogen sulfide: An endogenous regulator of the immune system.硫化氢：免疫系统的内源性调节剂。
Pharmacol Res. 2020 Nov;161:105119. doi: 10.1016/j.phrs.2020.105119. Epub 2020 Aug 8.
7
Metabolites released from apoptotic cells act as tissue messengers.凋亡细胞释放的代谢物作为组织信使发挥作用。
Nature. 2020 Apr;580(7801):130-135. doi: 10.1038/s41586-020-2121-3. Epub 2020 Mar 18.
8
Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1.Fas 通过结合和隔离转录因子 STAT1 促进辅助性 T 细胞 17 分化并抑制辅助性 T 细胞 1 发育。
Immunity. 2018 Mar 20;48(3):556-569.e7. doi: 10.1016/j.immuni.2018.03.008.
9
Hydrogen Sulfide Promotes Tet1- and Tet2-Mediated Foxp3 Demethylation to Drive Regulatory T Cell Differentiation and Maintain Immune Homeostasis.硫化氢促进Tet1和Tet2介导的Foxp3去甲基化，以驱动调节性T细胞分化并维持免疫稳态。
Immunity. 2015 Aug 18;43(2):251-63. doi: 10.1016/j.immuni.2015.07.017. Epub 2015 Aug 11.