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Mitochondrion quality control for longevity promotion.

作者信息

Zhang Yao, Chen Suzhen, Liu Junli

机构信息

Shanghai Diabetes Institute, Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

出版信息

Metabol Open. 2023 Oct 21;22:100259. doi: 10.1016/j.metop.2023.100259. eCollection 2024 Jun.

DOI:10.1016/j.metop.2023.100259
PMID:39011167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11247211/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bde5/11247211/19311f3eca0c/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bde5/11247211/19311f3eca0c/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bde5/11247211/19311f3eca0c/fx1.jpg

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本文引用的文献

1
Muscle PARP1 inhibition extends lifespan through AMPKα PARylation and activation in .肌肉 PARP1 抑制通过 AMPKα 的 PAR 化和激活延长寿命。
Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2213857120. doi: 10.1073/pnas.2213857120. Epub 2023 Mar 22.
2
Alternate therapeutic pathways for PARP inhibitors and potential mechanisms of resistance.聚腺苷二磷酸核糖聚合酶抑制剂的治疗选择途径和潜在耐药机制。
Exp Mol Med. 2021 Jan;53(1):42-51. doi: 10.1038/s12276-021-00557-3. Epub 2021 Jan 25.
3
Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress.
代谢。AMP 活化蛋白激酶在能量应激反应中介导线粒体分裂。
Science. 2016 Jan 15;351(6270):275-281. doi: 10.1126/science.aab4138.
4
Metformin improves healthspan and lifespan in mice.二甲双胍可改善小鼠的健康寿命和寿命。
Nat Commun. 2013;4:2192. doi: 10.1038/ncomms3192.
5
The hallmarks of aging.衰老的特征。
Cell. 2013 Jun 6;153(6):1194-217. doi: 10.1016/j.cell.2013.05.039.
6
Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies.腺苷核苷酸生物合成和 AMPK 调节成年寿命并介导热量限制对果蝇的长寿益处。
Cell Metab. 2013 Jan 8;17(1):101-12. doi: 10.1016/j.cmet.2012.12.006.
7
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation.PARP-1 抑制剂通过 SIRT1 的激活增加线粒体代谢。
Cell Metab. 2011 Apr 6;13(4):461-468. doi: 10.1016/j.cmet.2011.03.004.
8
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.AMPK 和钙调神经磷酸酶诱导的寿命延长是由 CRTC-1 和 CREB 介导的。
Nature. 2011 Feb 17;470(7334):404-8. doi: 10.1038/nature09706.
9
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity.AMPK通过调节NAD+代谢和SIRT1活性来调控能量消耗。
Nature. 2009 Apr 23;458(7241):1056-60. doi: 10.1038/nature07813.
10
Oxidative DNA damage repair and parp 1 and parp 2 expression in Epstein-Barr virus-immortalized B lymphocyte cells from young subjects, old subjects, and centenarians.年轻受试者、老年受试者和百岁老人的爱泼斯坦-巴尔病毒永生化B淋巴细胞中的氧化DNA损伤修复及PARP 1和PARP 2表达
Rejuvenation Res. 2007 Jun;10(2):191-204. doi: 10.1089/rej.2006.0514.