Perceived social support mediates cancer and living meaningfully intervention effects on quality of life after breast cancer surgery.

To explore the role of perceived social support in enhancing psychological resilience and quality of life in postoperative breast cancer patients. The Managing Cancer and Living Meaningfully (CALM) intervention was used to improve indicators such as psychological resilience in breast cancer patients, while the role of perceived social support in this was assessed. The intervention group exhibited significant improvements compared with the control group in psychological resilience (F = 9.059,  < 0.01). The analysis showed that increased social support in the control group partly mediated the link between psychological resilience and quality of life. CALM improves overall well-being, indicating that incorporating it into standard care for post-mastectomy patients can positively impact their mental health.