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体外肾-输尿管模型研究灌注冲洗对输尿管镜检查肾盂压力的虹吸效应影响。

The impact of siphoning effect on renal pelvis pressure during ureteroscopy using an in vitro kidney and ureter model.

机构信息

Department of Urology, Seoul National University Bundang Hospital, 82 Gumi-ro, 173 Beon-gil, Gumi-ro, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, South Korea.

Department of Urology, McLaren Macomb, Mt. Clemens, MI, USA.

出版信息

World J Urol. 2024 Jul 16;42(1):415. doi: 10.1007/s00345-024-05120-z.

Abstract

PURPOSE

To experimentally measure renal pelvis pressure (P) in an ureteroscopic model when applying a simple hydrodynamic principle, the siphoning effect.

METHODS

A 9.5Fr disposable ureteroscope was inserted into a silicone kidney-ureter model with its tip positioned at the renal pelvis. Irrigation was delivered through the ureteroscope at 100 cm above the renal pelvis. A Y-shaped adapter was fitted onto the model's renal pelvis port, accommodating a pressure sensor and a 4 Fr ureteral access catheter (UAC) through each limb. The drainage flowrate through the UAC tip was measured for 60 s each run. The distal tip of the UAC was placed at various heights below or above the center of the renal pelvis to create a siphoning effect. All trials were performed in triplicate for two lengths of 4Fr UACs: 100 cm and 70 cm (modified from 100 cm).

RESULTS

P was linearly dependent on the height difference from the center of the renal pelvis to the UAC tip for both tested UAC lengths. In our experimental setting, P can be reduced by 10 cmH0 simply by lowering the distal tip of a 4 Fr 70 cm UAC positioned alongside the ureteroscope by 19.7 cm. When using a 4 Fr 100 cm UAC, P can drop 10 cmH0 by lowering the distal tip of the UAC 23.3 cm below the level of the renal pelvis.

CONCLUSION

Implementing the siphoning effect for managing P during ureteroscopy could potentially enhance safety and effectiveness.

摘要

目的

通过应用虹吸效应这一简单的流体力学原理,在输尿管镜模型中实际测量肾盂压力(P)。

方法

将 9.5Fr 一次性输尿管镜插入带有肾盂的硅胶肾-输尿管模型中,使尖端位于肾盂处。通过输尿管镜在肾盂上方 100cm 处进行冲洗。在模型的肾盂端口上安装 Y 形适配器,通过每个分支容纳压力传感器和 4Fr 输尿管接入导管(UAC)。每次运行时测量 UAC 尖端的引流流速 60 秒。将 UAC 的远端尖端放置在肾盂中心下方或上方的不同高度,以产生虹吸效应。所有试验均重复进行三次,使用两种长度的 4Fr UAC:100cm 和 70cm(从 100cm 改短)。

结果

对于两种测试的 UAC 长度,P 与从肾盂中心到 UAC 尖端的高度差呈线性相关。在我们的实验设置中,通过将并排放置的 4Fr 70cm UAC 的远端尖端降低 19.7cm,即可将 P 降低 10cmH0。使用 4Fr 100cm UAC 时,通过将 UAC 的远端尖端降低至肾盂以下 23.3cm,可将 P 降低 10cmH0。

结论

在输尿管镜检查期间实施虹吸效应来管理 P,可能会提高安全性和有效性。

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