IEEE Trans Biomed Eng. 2024 Nov;71(11):3244-3251. doi: 10.1109/TBME.2024.3414607. Epub 2024 Oct 25.
Magneto-acousto-electrical tomography (MAET) is a hybrid imaging method that combines the high spatial resolution of ultrasonography with the high contrast of electrical impedance tomography (EIT). While most previous studies on MAET have focused on two-dimensional imaging, our recent research proposed a novel three-dimensional (3D) MAET method using B-mode and translational scanning. This method has been the first to reconstruct a 3D volume image of conductivity interfaces. However, this method has its limitations in mapping irregular shapes of conductivity. To address this challenge, we propose a 3D magneto-acousto-electrical computed tomography (3D MAE-CT) method utilizing an ultrasound linear array transducer in this work. Both phantom and in vitro experiments were conducted to validate our proposed method. The results from the phantom experiments demonstrate that our method can map the 3D volume conductivity with high spatial resolution. The oblique angles extracted from the 3D image closely match practical value, with the relative error ranging between -2.80% and 4.07%. Furthermore, the in vitro experiment successfully obtained a 3D image of a chicken heart, marking the first MAET 3D conductivity image of a tissue sample to date.
磁声电层析成像(MAET)是一种混合成像方法,它结合了超声的高空间分辨率和电阻抗断层成像(EIT)的高对比度。虽然之前的大多数 MAET 研究都集中在二维成像上,但我们最近的研究提出了一种使用 B 模式和平移扫描的新型三维(3D)MAET 方法。该方法首次重建了电导率界面的 3D 体积图像。然而,该方法在绘制不规则形状的电导率方面存在局限性。为了解决这个挑战,我们在这项工作中提出了一种利用超声线阵换能器的 3D 磁声电计算机层析成像(3D MAE-CT)方法。进行了体模和离体实验来验证我们提出的方法。体模实验的结果表明,我们的方法可以以高空间分辨率绘制 3D 体积电导率。从 3D 图像中提取的斜角与实际值非常吻合,相对误差在-2.80%到 4.07%之间。此外,离体实验成功获得了鸡心的 3D 图像,这是迄今为止组织样本的第一个 MAET 3D 电导率图像。