Sultanova Alina, Sokolovska Liba, Cistjakovs Maksims, Lifsics Andrejs
Institute of Microbiology and Virology Riga Stradiņš University, Rātsupītes 5 LV-1067, Riga, Latvia.
Department of Otorhinolaryngology Riga Stradiņš University, Pilsoņu 13 LV-1002, Riga, Latvia.
Case Rep Infect Dis. 2024 Jul 8;2024:6044987. doi: 10.1155/2024/6044987. eCollection 2024.
Laryngeal papillomatosis (LP) is the most common benign laryngeal tumor in children, but it can affect both children and adults. Although benign, this condition still remains hard to treat and negatively affects patient quality of life as it can spread to the adjacent respiratory tract, recurs, and requires repeated medical intervention. As the surgical removal of papillomas with the preservation of normal mucosa is the only standard of care, there is still no standard for adjuvant therapy. In this case report, we describe the course of recurrent laryngeal papillomatosis in a Caucasian male from 2009 to 2016 and the positive response to dsRNA-based antiviral drug treatment in the complete resolvement of the condition.
喉乳头状瘤病（LP）是儿童中最常见的喉部良性肿瘤，但它可影响儿童和成人。尽管是良性的，但这种疾病仍然难以治疗，并且会对患者的生活质量产生负面影响，因为它可扩散至相邻的呼吸道，会复发，并且需要反复进行医学干预。由于在保留正常黏膜的情况下手术切除乳头状瘤是唯一的治疗标准，目前仍然没有辅助治疗的标准。在本病例报告中，我们描述了一名白人男性在2009年至2016年期间复发性喉乳头状瘤病的病程，以及基于双链RNA的抗病毒药物治疗对该疾病完全缓解的积极反应。
