Jarrett Simone A, Talati Rushi Kaushik, Hasbun Johann, Cao Wenqing, Smukalla Scott M
Department of Internal Medicine, Albert Einstein Medical Center, Philadelphia, PA, USA.
Sidney Kimmel College of Thomas Jefferson University, Philadelphia, PA, USA.
Case Rep Gastroenterol. 2024 Jun 7;18(1):306-312. doi: 10.1159/000538965. eCollection 2024 Jan-Dec.
Acute upper gastrointestinal bleeding is one of the most common medical emergencies that present to the hospital, and delineating the underlying etiology is essential to provide adequate definitive treatment. The purpose of this case report was to review the diagnosis and treatment of a rare complication known as radiation-induced hemorrhagic gastritis (RIHG) that can occur in patients with prior radiation exposure. The motivation for this study arose from the identification of a case within our institution.
The study involved a review of the diagnosis and management of a patient who presented with anemia and recurrent episodes of gastrointestinal bleeding at our institution after undergoing treatment for metastatic biliary adenocarcinoma. With the advent of new therapies, we aimed to investigate the various techniques utilized to manage these patients and highlight the importance of maintaining a high index of suspicion for RIHG as a potential etiology of gastrointestinal bleeding in patients with a relevant medical history of radiation exposure. Despite the literature review, we found that there is a lack of guidelines in the approach to the management of these patients.
This case report underscores the rarity of radiation-induced gastritis and the complications that may arise from its diagnosis, including recurrent GI bleeding. Further investigation into identifying definitive treatment and creating guidelines for its management is desperately needed.
急性上消化道出血是最常见的需住院治疗的内科急症之一,明确潜在病因对于提供充分的确定性治疗至关重要。本病例报告的目的是回顾一种罕见并发症——放射性出血性胃炎(RIHG)的诊断和治疗,该并发症可发生于既往有放疗史的患者。本研究的动机源于我们机构内确诊的一例病例。
该研究回顾了我院一名转移性胆管腺癌患者在接受治疗后出现贫血和反复胃肠道出血的诊断及管理情况。随着新疗法的出现,我们旨在研究用于治疗这些患者的各种技术,并强调对于有放疗相关病史的患者,高度怀疑RIHG为胃肠道出血潜在病因的重要性。尽管进行了文献综述,但我们发现对于这些患者的管理缺乏指导原则。
本病例报告强调了放射性胃炎的罕见性及其诊断可能引发的并发症,包括反复胃肠道出血。迫切需要进一步研究以确定确定性治疗方法并制定其管理指南。