Jarrett Simone A, Tito Sahana, Chan Matthew, Jarrett Dominic E, Lo Kevin B, DePalma Richard
Department of Internal Medicine, Albert Einstein Medical Center, Philadelphia, PA, USA.
Sidney Kimmel College of Thomas Jefferson University, Philadelphia, PA, USA.
Case Rep Gastroenterol. 2024 Jan 9;18(1):14-20. doi: 10.1159/000534973. eCollection 2024 Jan-Dec.
The purpose of this case series was to review a rare subset of tumors known as gastric lipomas, which are typically found incidentally. The motivation for this study arose from the identification of 2 cases within our institution in a short period.
The study involved a review of the diagnosis and management of 2 patients presenting with gastric lipomas at our institution after symptoms of gastrointestinal bleeding. With the advent of new radiologic investigations such as computed tomography and magnetic resonance imaging and advances in endoscopy, there are new approaches to identifying and managing these tumors. On further evaluation of the literature, we found that despite the availability of minimally invasive endoscopic techniques such as mucosal resection and submucosal dissection in the setting of large tumors, most patients tend to have to resort to surgical management.
This case series underscores the rarity of gastric lipomas and their often-incidental discovery. Further investigation into endoscopic approaches for managing these tumors is needed, and additionally, there is a need to explore a potential association between gastric lipomas and malignancy, as chronic inflammation of the overlying mucosa may play a significant role.
本病例系列的目的是回顾一类罕见的肿瘤,即胃脂肪瘤,这类肿瘤通常是偶然发现的。本研究的动机源于我们机构在短时间内确诊的2例病例。
本研究回顾了我院2例出现胃肠道出血症状后被诊断为胃脂肪瘤的患者的诊断和治疗情况。随着计算机断层扫描和磁共振成像等新的放射学检查方法的出现以及内镜技术的进步,出现了识别和处理这些肿瘤的新方法。在进一步查阅文献时,我们发现,尽管对于较大的肿瘤可以采用黏膜切除和黏膜下剥离等微创内镜技术,但大多数患者往往仍需采取手术治疗。
本病例系列强调了胃脂肪瘤的罕见性及其常常偶然被发现的特点。需要进一步研究内镜治疗这些肿瘤的方法,此外,还需要探讨胃脂肪瘤与恶性肿瘤之间的潜在关联,因为覆盖其上的黏膜的慢性炎症可能起重要作用。