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转移性去势抵抗性前列腺癌的息肉样大肠受累:一例报告

Polypoid Large Intestinal Involvement of Metastatic Castrate-Resistant Prostate Cancer: A Case Report.

作者信息

Narayanan Sathya, Dvuchbabny Sapir, Arzivian Arteen, Kim Sang, Cheng Robert, Gurney Howard

机构信息

Macquarie University Hospital, Sydney, NSW, Australia.

Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW, Australia.

出版信息

Case Rep Oncol. 2024 Jul 11;17(1):717-724. doi: 10.1159/000539783. eCollection 2024 Jan-Dec.

Abstract

INTRODUCTION

Prostate cancer most commonly metastasizes to the bone and lymph nodes. Gastrointestinal metastasis has been noted in the literature but appears to be an exceedingly uncommon phenomenon. Large intestinal involvement in particular has been reported on only a few occasions, and never concomitantly with small intestinal metastatic involvement.

CASE REPORT

We report the case of a 69-year-old gentleman with metastatic castrate-resistant prostate cancer with development of gastrointestinal symptomatology with extensive investigation eventually revealing small and large intestinal polyps subsequently confirmed to be representative of metastatic prostate cancer.

CONCLUSION

This case demonstrates the importance of maintaining a wide differential diagnosis in the context of gastrointestinal symptomatology in malignancy. Thorough endoscopic evaluation may be necessary in such cases in order to identify potential metastatic malignancy in otherwise relatively unremarkable appearing polyps.

摘要

引言

前列腺癌最常转移至骨骼和淋巴结。胃肠道转移在文献中已有记载,但似乎是一种极为罕见的现象。特别是大肠受累仅在少数情况下有报道,且从未与小肠转移受累同时出现。

病例报告

我们报告一例69岁男性,患有转移性去势抵抗性前列腺癌,出现胃肠道症状,经过广泛检查最终发现小肠和大肠息肉,随后证实这些息肉为转移性前列腺癌。

结论

本病例表明,在恶性肿瘤出现胃肠道症状的情况下,保持广泛的鉴别诊断非常重要。在此类病例中,可能需要进行全面的内镜评估,以便在外观相对正常的息肉中识别潜在的转移性恶性肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8551/11250128/225a22cf4493/cro-2024-0017-0001-539783_F01.jpg

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