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患者与药剂师的关系动态:患者特征与报告结果的中介分析

Patient-pharmacist relationship dynamics: a mediation analysis of patient characteristics and reported outcomes.

作者信息

Sacre Hala, Haddad Chadia, Sakr Fouad, Safwan Jihan, Hajj Aline, Zeenny Rony M, Akel Marwan, Salameh Pascale

机构信息

INSPECT-LB (Institut National de Santé Publique, d'Épidémiologie Clinique et de Toxicologie-Liban), Beirut, Lebanon.

School of Medicine, Lebanese American University, Byblos, Lebanon.

出版信息

J Pharm Policy Pract. 2024 Jul 15;17(1):2371409. doi: 10.1080/20523211.2024.2371409. eCollection 2024.

Abstract

BACKGROUND

While previous research underscores the independent effect of the pharmacist-patient relationship on patient outcomes, it did not delve further into the patient-pharmacist relationship dynamics and their effects on reported outcomes. Therefore, this study aimed to assess whether patient-pharmacist relationship aspects mediate the association between patient personal and health characteristics, on the one hand, and adherence to medication and quality of life, on the other hand (QOL).

METHODS

An online cross-sectional study was conducted between April 11 and 27, 2023. It enrolled 865 adults from all Lebanese governorates and used validated scales to measure the various concepts.

RESULTS

The mean age was 32.52 ± 14.56 years, and 68.8% were female. Also, 79.3% reported having no chronic disease, and 57.7% indicated that getting nonprescription medications was the main reason for visiting a community pharmacy. The average routine intake of medications per day was 0.87 ± 1.78. Our key findings reveal a compelling association between worse health status and both increased medication non-adherence and reduced QOL. Sociodemographic factors were found to be correlated with QOL. Despite the considerable impact of demographic factors on patient expectations, our study challenges the expected mediation role of the pharmacist-patient relationship and counseling time on medication adherence. Nevertheless, patient expectations partially mediated the relationship between sociodemographic characteristics and QOL.

CONCLUSION

This study sheds light on the intricate dynamics between patient characteristics, health status, medication adherence, and QOL within the context of the patient-pharmacist relationships.

摘要

背景

虽然先前的研究强调了药师与患者关系对患者结局的独立影响,但并未进一步深入探讨患者与药师关系的动态变化及其对报告结局的影响。因此,本研究旨在评估患者与药师关系的各个方面是否一方面介导患者个人和健康特征与另一方面的药物依从性和生活质量(QOL)之间的关联。

方法

于2023年4月11日至27日进行了一项在线横断面研究。该研究招募了来自黎巴嫩所有省份的865名成年人,并使用经过验证的量表来测量各种概念。

结果

平均年龄为32.52±14.56岁,68.8%为女性。此外,79.3%的人报告没有慢性病,57.7%的人表示购买非处方药是访问社区药房的主要原因。每天药物的平均常规摄入量为0.87±1.78。我们的主要发现揭示了较差的健康状况与药物不依从性增加和生活质量降低之间存在显著关联。发现社会人口统计学因素与生活质量相关。尽管人口统计学因素对患者期望有相当大的影响,但我们的研究对药师与患者关系和咨询时间对药物依从性的预期中介作用提出了挑战。然而,患者期望部分介导了社会人口统计学特征与生活质量之间的关系。

结论

本研究揭示了在患者与药师关系背景下患者特征、健康状况、药物依从性和生活质量之间的复杂动态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f029/11251441/4675ca5098bc/JPPP_A_2371409_F0001_OB.jpg

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