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一种罕见的并存情况:贲门失弛缓症食管与急性假性肠梗阻。

A Rare Coexistence: Achalasia Esophagus and Acute Intestinal Pseudo-Obstruction.

作者信息

Kyvetos Andreas, Manoli Anastasia, Voukelatou Panagiota, Theodoropoulou Theoni, Vrettos Ioannis

机构信息

2nd Department of Internal Medicine, General and Oncology Hospital of Kifissia "Agioi Anargyroi", Athens, GRC.

2nd Department of Pediatrics, Pendelis General Children's Hospital, Athens, GRC.

出版信息

Cureus. 2024 Jun 16;16(6):e62489. doi: 10.7759/cureus.62489. eCollection 2024 Jun.

DOI:10.7759/cureus.62489
PMID:39015875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11251737/
Abstract

Achalasia esophagus and acute intestinal pseudo-obstruction are distinct gastrointestinal motility disorders rarely found together in the same patient. We present a case of a 96-year-old woman exhibiting symptoms of both conditions, including dysphagia, regurgitation, abdominal distension, nausea, vomiting, and constipation. Diagnostic evaluations revealed esophageal dilation with a "bird beak" sign on timed barium swallows and significant bowel dilation without mechanical obstruction on computed tomography scans. Treatment involved conservative measures for acute intestinal pseudo-obstruction and palliative approaches for achalasia esophagus. The coexistence of these disorders raises questions about potential shared pathophysiological mechanisms involving the enteric nervous system or smooth muscle dysfunction. Further research is warranted to elucidate these connections and improve management strategies for such complex cases.

摘要

贲门失弛缓症和急性假性肠梗阻是不同的胃肠动力障碍,很少在同一患者中同时出现。我们报告一例96岁女性同时出现这两种疾病的症状,包括吞咽困难、反流、腹胀、恶心、呕吐和便秘。诊断评估显示,在定时钡餐检查中食管扩张呈“鸟嘴”征,计算机断层扫描显示肠道明显扩张但无机械性梗阻。治疗包括针对急性假性肠梗阻的保守措施和针对贲门失弛缓症的姑息治疗方法。这些疾病的共存引发了关于涉及肠神经系统或平滑肌功能障碍的潜在共同病理生理机制的问题。有必要进行进一步研究以阐明这些联系,并改善此类复杂病例的管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cac/11251737/6c4953cf3ba0/cureus-0016-00000062489-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cac/11251737/df6dedd381d0/cureus-0016-00000062489-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cac/11251737/09abf4aaad63/cureus-0016-00000062489-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cac/11251737/6c4953cf3ba0/cureus-0016-00000062489-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cac/11251737/df6dedd381d0/cureus-0016-00000062489-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cac/11251737/09abf4aaad63/cureus-0016-00000062489-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cac/11251737/6c4953cf3ba0/cureus-0016-00000062489-i03.jpg

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本文引用的文献

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Development of Achalasia in a Patient With Chronic Intestinal Pseudo-Obstruction.一名慢性肠道假性梗阻患者发生贲门失弛缓症
ACG Case Rep J. 2022 Jun 3;9(6):e00758. doi: 10.14309/crj.0000000000000758. eCollection 2022 Jun.
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ACG Clinical Guidelines: Diagnosis and Management of Achalasia.ACG 临床指南:贲门失弛缓症的诊断与管理。
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Bird's beak sign: Achalasia.鸟嘴征:贲门失弛缓症。
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