Kim Tae Nam, Kim Ahrong, Kim Kyung Bin, Lee Chang Hun
Department of Urology, Pusan National University, School of Medicine, Biomedical Research Institute and Pusan National University Hospital, Busan 43241, South Korea.
Department of Pathology, Pusan National University, School of Medicine, Busan 49241, South Korea.
World J Clin Cases. 2024 Jul 16;12(20):4412-4418. doi: 10.12998/wjcc.v12.i20.4412.
Cases of severe inflammatory renal disease and renal cell carcinoma (RCC) that occur simultaneously in the same kidney have been occasionally reported. However, extrarenal RCC that does not originate from the native kidney has rarely been reported. To our knowledge, this is the first reported case of RCC developing in the ipsilateral retroperitoneal space after a simple nephrectomy (SN) for inflammatory renal disease.
A 63-year-old woman was referred to our hospital following the incidental discovery of a left retroperitoneal mass without specific symptoms. Her medical history revealed a left SN 27 years ago due to a renal abscess. Magnetic resonance imaging of the abdomen revealed three oval masses in the left retroperitoneum. The masses were successfully excised, and subsequent pathology confirmed papillary RCC. After surgery, the patient remained disease-free for 11 years without adjuvant therapy.
Clinicians should be vigilant of RCC in patients with retroperitoneal masses, especially after SN for inflammatory renal disease.
同一肾脏中同时发生严重炎症性肾病和肾细胞癌(RCC)的病例偶尔有报道。然而,并非起源于天然肾脏的肾外RCC很少被报道。据我们所知,这是首例在因炎症性肾病行单纯肾切除术(SN)后,同侧腹膜后间隙发生RCC的报道。
一名63岁女性因偶然发现左侧腹膜后肿块且无特定症状而转诊至我院。她的病史显示27年前因肾脓肿行左侧SN。腹部磁共振成像显示左侧腹膜后有三个椭圆形肿块。这些肿块被成功切除,随后的病理证实为乳头状RCC。术后,患者未接受辅助治疗,无病生存11年。
临床医生应对腹膜后肿块患者,尤其是因炎症性肾病行SN后的患者警惕RCC。