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澳门蛛网膜下腔出血的一种罕见病因——基底动脉穿支动脉瘤:三例报告并文献复习

An unusual etiology of subarachnoid hemorrhage, basilar artery perforator aneurysms, in Macao: Three case reports and review of literature.

作者信息

Man Ieong-Chon, Pan Tam-Man, U Kuok-Cheong

机构信息

Department of Radiology, Hospital Conde S. Januário, Macao SAR 999078, China.

出版信息

World J Clin Cases. 2024 Jul 16;12(20):4337-4347. doi: 10.12998/wjcc.v12.i20.4337.

DOI:10.12998/wjcc.v12.i20.4337
PMID:39015907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11235533/
Abstract

BACKGROUND

Subarachnoid hemorrhage is a severe neurological condition that requires prompt and appropriate treatment to prevent complications. Aneurysms are the most common cause of spontaneous subarachnoid hemorrhage. Conversely, basilar artery perforator aneurysms (BAPAs) are a rare etiology. There is no consensus on the optimal management of ruptured BAPAs in the acute setting.

CASE SUMMARY

We present a case series of 3 patients with ruptured BAPAs who were treated at our institution. Two patients had a modified Fisher grade of I, and one had a grade of IV on initial presentation. The aneurysms were detected by computed tomography angiography in two cases and conventional angiography in one case. The 3 patients underwent endovascular treatment with Guglielmi detachable coils. Post-treatment, the patients had good clinical outcomes, and follow-up brain computed tomography scans showed reduced subarachnoid hemorrhage without any new hemorrhage. However, one patient experienced a cerebral infarction 2 months later and eventually succumbed to the condition. The other 2 patients showed progressive recovery, and no aneurysm recurrence was observed at the 2-year follow-up.

CONCLUSION

Endovascular treatment may be a preferable approach for managing ruptured BAPAs compared with surgical intervention or conservative management. Early detection and prompt treatment is important to achieve favorable patient outcomes.

摘要

背景

蛛网膜下腔出血是一种严重的神经系统疾病,需要及时且恰当的治疗以预防并发症。动脉瘤是自发性蛛网膜下腔出血最常见的病因。相反,基底动脉穿支动脉瘤(BAPA)是一种罕见的病因。对于急性情况下破裂的BAPA的最佳治疗方法尚无共识。

病例总结

我们报告了在我院接受治疗的3例破裂BAPA患者的病例系列。2例患者初始表现为改良Fisher分级I级,1例为IV级。2例通过计算机断层扫描血管造影术检测到动脉瘤,1例通过传统血管造影术检测到。这3例患者均接受了使用 Guglielmi 可解脱弹簧圈的血管内治疗。治疗后,患者临床预后良好,随访脑部计算机断层扫描显示蛛网膜下腔出血减少,无新的出血。然而,1例患者在2个月后发生脑梗死,最终死亡。另外2例患者病情逐渐恢复,在2年随访中未观察到动脉瘤复发。

结论

与手术干预或保守治疗相比,血管内治疗可能是治疗破裂BAPA的更优方法。早期发现和及时治疗对于取得良好的患者预后很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8b2/11235533/27596c8bafc4/WJCC-12-4337-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8b2/11235533/4bdd51a0e457/WJCC-12-4337-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8b2/11235533/5d39f86d35c9/WJCC-12-4337-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8b2/11235533/7acc4bf70cf4/WJCC-12-4337-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8b2/11235533/27596c8bafc4/WJCC-12-4337-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8b2/11235533/4bdd51a0e457/WJCC-12-4337-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8b2/11235533/5d39f86d35c9/WJCC-12-4337-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8b2/11235533/7acc4bf70cf4/WJCC-12-4337-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8b2/11235533/27596c8bafc4/WJCC-12-4337-g004.jpg

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