Tang Wen-Wen, Han Mei-Lin, Xu Shu-Hua, Deng You-Xing, Shen Qiao
Department of Oncology, Hefei BOE Hospital, Hefei 230011, Anhui Province, China.
Department of Nursing, Hefei BOE Hospital, Hefei 230011, Anhui Province, China.
World J Clin Cases. 2024 Jul 16;12(20):4247-4255. doi: 10.12998/wjcc.v12.i20.4247.
Colorectal cancer is the second leading cause of cancer-related deaths among digestive tract malignancies, following gastric cancer. Sleep is of great significance for maintaining human health. The incidence of sleep disorders in patients with cancer is approximately twice that observed in the general population. Lack of sleep can prolong hospital stays, increase the likelihood of infection, and increase mortality rates. Therefore, studying the factors related to sleep quality is significant for improving the quality of life of patients with malignant tumors of the digestive tract.
To investigate the relationships among sleep quality, disease uncertainty, and psychological resilience in patients undergoing chemotherapy for digestive tract malignancies.
A total of 131 patients with malignant digestive tract tumors who were treated at Hefei BOE Hospital between April 2021 and September 2022 were selected as research participants. Based on their Pittsburgh Sleep Quality Index (PSQI) scores, participants were divided into either the sleep disorder group (PSQI score > 7) or the normal sleep group (PSQI score ≤ 7). The clinical data-together with the Mishel Uncertainty in Illness Scale for Adults (MUIS-A) and Connor-Davidson Resilience Scale (CD-RISC) scores-were compared.
In this study, 78 (59.54%) patients with digestive tract malignancies developed sleep disorders after chemotherapy. Sleep disorder incidence was higher in patients with colorectal cancer than in those with gastric and esophageal cancers ( < 0.05). The total MUIS-A score and those for each item in the sleep disorder group were higher than those in the normal sleep group. The total CD-RISC score and those for each item in the sleep disorder group were lower than those in the normal sleep group ( < 0.05). The PSQI scores of patients with malignant digestive tract tumors were positively correlated with the scores for lack of disease information, disease uncertainty, and unpredictability in the MUIS-A and negatively correlated with the scores for tenacity, self-improvement, and optimism in the CD-RISC ( < 0.05).
Patients undergoing chemotherapy for digestive tract malignancies are prone to sleep problems related to disease uncertainty and psychological resilience. Therefore, interventions can be implemented to improve their sleep quality.
结直肠癌是继胃癌之后消化道恶性肿瘤中癌症相关死亡的第二大主要原因。睡眠对于维持人类健康具有重要意义。癌症患者睡眠障碍的发生率约为普通人群的两倍。睡眠不足会延长住院时间，增加感染几率，并提高死亡率。因此，研究与睡眠质量相关的因素对于改善消化道恶性肿瘤患者的生活质量具有重要意义。
探讨消化道恶性肿瘤化疗患者睡眠质量、疾病不确定感和心理弹性之间的关系。
选取2021年4月至2022年9月在合肥京东方医院接受治疗的131例消化道恶性肿瘤患者作为研究对象。根据匹兹堡睡眠质量指数（PSQI）得分，将参与者分为睡眠障碍组（PSQI得分>7）或正常睡眠组（PSQI得分≤7）。比较临床资料以及成人疾病不确定感量表（MUIS-A）和康纳-戴维森心理弹性量表（CD-RISC）得分。
本研究中，78例（59.54%）消化道恶性肿瘤患者化疗后出现睡眠障碍。结直肠癌患者的睡眠障碍发生率高于胃癌和食管癌患者（<0.05）。睡眠障碍组的MUIS-A总分及各项目得分均高于正常睡眠组。睡眠障碍组的CD-RISC总分及各项目得分均低于正常睡眠组（<0.05）。消化道恶性肿瘤患者的PSQI得分与MUIS-A中疾病信息缺乏、疾病不确定感和不可预测性得分呈正相关，与CD-RISC中坚韧、自我提升和乐观得分呈负相关（<0.05）。
消化道恶性肿瘤化疗患者容易出现与疾病不确定感和心理弹性相关的睡眠问题。因此，可以采取干预措施来改善他们的睡眠质量。
