Yang Hai, Gao Li-Jun, Lei Jing, Li Qiang, Cui Liu, Li Xiao-Hua, Yin Wu-Xuan, Tian Sen-Hua
Neonatal Intensive Care Center, Liupanshui Maternal and Child Care Service Center, Liupanshui 553000, Guizhou Province, China.
Ultrasound Function Department, Liupanshui Maternal and Child Care Service Center, Liupanshui 553000, Guizhou Province, China.
World J Clin Cases. 2024 Jul 16;12(20):4154-4165. doi: 10.12998/wjcc.v12.i20.4154.
Accurate condition assessment is critical for improving the prognosis of neonatal respiratory distress syndrome (RDS), but current assessment methods for RDS pose a cumulative risk of harm to neonates. Thus, a less harmful method for assessing the health of neonates with RDS is needed.
To analyze the relationships between pulmonary ultrasonography and respiratory distress scores, oxygenation index, and chest X-ray grade of neonatal RDS to identify predictors of neonatal RDS severity.
This retrospective study analyzed the medical information of 73 neonates with RDS admitted to the neonatal intensive care unit of Liupanshui Maternal and Child Care Service Center between April and December 2022. The pulmonary ultrasonography score, respiratory distress score, oxygenation index, and chest X-ray grade of each newborn before and after treatment were collected. Spearman correlation analysis was performed to determine the relationships among these values and neonatal RDS severity.
The pulmonary ultrasonography score, respiratory distress score, oxygenation index, and chest X-ray RDS grade of the neonates were significantly lower after treatment than before treatment ( < 0.05). Spearman correlation analysis showed that before and after treatment, the pulmonary ultrasonography score of neonates with RDS was positively correlated with the respiratory distress score, oxygenation index, and chest X-ray grade ( = 0.429-0.859, < 0.05). Receiver operating characteristic curve analysis indicated that pulmonary ultrasonography screening effectively predicted the severity of neonatal RDS (area under the curve = 0.805-1.000, < 0.05).
The pulmonary ultrasonography score was significantly associated with the neonatal RDS score, oxygenation index, and chest X-ray grade. The pulmonary ultrasonography score was an effective predictor of neonatal RDS severity.
准确的病情评估对于改善新生儿呼吸窘迫综合征（RDS）的预后至关重要，但目前用于RDS的评估方法对新生儿存在累积伤害风险。因此，需要一种对患有RDS的新生儿危害较小的健康评估方法。
分析肺部超声与新生儿RDS的呼吸窘迫评分、氧合指数及胸部X线分级之间的关系，以确定新生儿RDS严重程度的预测指标。
这项回顾性研究分析了2022年4月至12月期间在六盘水市妇幼保健服务中心新生儿重症监护病房收治的73例RDS新生儿的医疗信息。收集了每个新生儿治疗前后的肺部超声评分、呼吸窘迫评分、氧合指数及胸部X线分级。采用Spearman相关性分析来确定这些值与新生儿RDS严重程度之间的关系。
治疗后，新生儿的肺部超声评分、呼吸窘迫评分、氧合指数及胸部X线RDS分级均显著低于治疗前（<0.05）。Spearman相关性分析显示，治疗前后，患有RDS的新生儿肺部超声评分与呼吸窘迫评分、氧合指数及胸部X线分级呈正相关（=0.429 - 0.859，<0.05）。受试者工作特征曲线分析表明，肺部超声筛查能有效预测新生儿RDS的严重程度（曲线下面积 = 0.805 - 1.000，<0.05）。
肺部超声评分与新生儿RDS评分、氧合指数及胸部X线分级显著相关。肺部超声评分是新生儿RDS严重程度的有效预测指标。
