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神经内镜手术中的荧光染料。

Fluorophores in Endoscopic Neurosurgery.

机构信息

Department of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Adv Tech Stand Neurosurg. 2024;52:21-28. doi: 10.1007/978-3-031-61925-0_3.

DOI:10.1007/978-3-031-61925-0_3
PMID:39017784
Abstract

The complexity of intracranial anatomy and pathologies warrants the optimization of multimodal techniques to ensure safe and effective surgical treatment. Endoscopy is being more widely implemented in intracranial procedures as an important visualization tool, as it can offer panoramic views of deep structures while reducing the invasiveness of approaches. Fluorophores are frequently utilized to augment the identification of intracranial anatomic landmarks and pathologies. This chapter discusses the integration of these two surgical adjuncts, highlighting the key fluorophores used in endoscopic neurosurgery and their clinical applications.

摘要

颅内解剖结构和病变的复杂性要求优化多种模态技术,以确保安全有效的手术治疗。内窥镜检查作为一种重要的可视化工具,在颅内手术中得到了更广泛的应用,因为它可以提供深部结构的全景视图,同时减少手术入路的侵袭性。荧光剂经常被用来增强颅内解剖标志和病变的识别。本章讨论了这两种手术辅助手段的整合,重点介绍了在神经内镜手术中使用的关键荧光剂及其临床应用。

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本文引用的文献

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From white to blue light: evolution of endoscope-assisted intracranial tumor neurosurgery and expansion to intraaxial tumors.从白光到蓝光:神经内镜辅助颅内肿瘤手术的演变及对颅内肿瘤的拓展
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Indocyanine Green Endoscopy for Pituitary Adenomas with Parasellar Extension: Results from a Preliminary Case Series.鞍旁延伸垂体腺瘤的吲哚菁绿内镜检查:初步病例系列研究结果。
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Indocyanine Green-Assisted Endoscopic Transorbital Excision of Lateral Orbital Apex Cavernous Hemangioma.
吲哚菁绿辅助内镜经眶外侧尖颅底海绵状血管瘤切除术。
World Neurosurg. 2022 Feb;158:167. doi: 10.1016/j.wneu.2021.11.060. Epub 2021 Nov 20.
4
5-ALA Enhanced Fluorescence-Guided Microscopic to Endoscopic Resection of Deep Frontal Subcortical Glioblastoma Multiforme.5-ALA 增强荧光引导显微镜至内镜下切除深部额皮质下多形性胶质母细胞瘤。
World Neurosurg. 2021 Apr;148:65. doi: 10.1016/j.wneu.2020.12.168. Epub 2021 Jan 13.
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Fluorescence Guidance and Intraoperative Adjuvants to Maximize Extent of Resection.荧光引导和术中辅助以最大限度地扩大切除范围。
Neurosurgery. 2021 Oct 13;89(5):727-736. doi: 10.1093/neuros/nyaa475.
6
Fluorescein Sodium-Guided Neuroendoscopic Resection of Deep-Seated Malignant Brain Tumors: Preliminary Results of 18 Patients.荧光素钠引导下神经内镜切除深部恶性脑肿瘤:18例患者的初步结果
Oper Neurosurg. 2021 Jan 13;20(2):206-218. doi: 10.1093/ons/opaa313.
7
Tricks and traps of ICG endoscopy for effectively applying endoscopic transsphenoidal surgery to pituitary adenoma.吲哚菁绿内镜在垂体腺瘤内镜经蝶窦手术有效应用中的技巧与陷阱
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Application of indocyanine green fluorescence endoscopic system in transsphenoidal surgery for pituitary tumors.吲哚菁绿荧光内镜系统在经蝶窦垂体瘤手术中的应用。
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9
Surgery of Small Anterior Skull Base Meningiomas by Endoscopic 5-Aminolevulinic Acid Fluorescence Guidance: First Clinical Experience.内镜下5-氨基酮戊酸荧光引导下的前颅底小型脑膜瘤手术:首例临床经验
World Neurosurg. 2019 Feb;122:e890-e895. doi: 10.1016/j.wneu.2018.10.171. Epub 2018 Nov 10.
10
Near-Infrared Optical Contrast of Skull Base Tumors During Endoscopic Endonasal Surgery.内镜经鼻颅底手术中颅底肿瘤的近红外光学对比。
Oper Neurosurg (Hagerstown). 2019 Jul 1;17(1):32-42. doi: 10.1093/ons/opy213.