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微血管游离骨皮瓣在放射性复发性口腔癌治疗中的应用。

Application of microvascular free osteocutaneous flaps in the management of post-radiation recurrent oral cancer.

作者信息

Rosen I B, Manktelow R T, Zuker R M, Boyd B

出版信息

Am J Surg. 1985 Oct;150(4):474-9. doi: 10.1016/0002-9610(85)90157-6.

Abstract

Fifty-nine patients underwent free flap osteocutaneous reconstruction that consisted of flaps of the dorsum of the foot in 26 patients and iliac crest flaps in 33 with a success rate of 92 percent and a mortality rate of 1.6 percent. These flaps, which require the expertise of microvascular surgeons, are time-consuming and complicate operating room and time management, but they represent a remarkable advance in reconstruction that can facilitate cosmetic and functional recovery of the patient. In particular, they promote healing in radiation-recurrent oral cancer and represent a definitive form of management for established radionecrosis of the mandible. The large volume of tissue available with iliac crest osteocutaneous grafts permits the management of patients with extensive cancer involving the skin, mucosa, and bone, but cancer control may still be disappointing and there is a need for improved adjuvant chemotherapy protocols. This technique appears to be a dependable, repeatable, and significant advance in management of the patient with head and neck cancer.

摘要

59例患者接受了游离皮瓣骨皮瓣重建术,其中26例采用足背皮瓣,33例采用髂嵴皮瓣,成功率为92%,死亡率为1.6%。这些皮瓣需要微血管外科医生的专业技术,耗时且使手术室和时间管理变得复杂,但它们代表了重建领域的显著进步,可促进患者的美容和功能恢复。特别是,它们能促进放射性复发性口腔癌的愈合,是已确诊的下颌骨放射性骨坏死的一种确定性治疗方式。髂嵴骨皮瓣可提供大量组织,适用于治疗累及皮肤、黏膜和骨骼的广泛癌症患者,但癌症控制效果可能仍不尽人意,因此需要改进辅助化疗方案。这项技术似乎是头颈癌患者治疗中的一项可靠、可重复且重大的进展。

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