Jafari Reza, Shushtari Ali, Ahmadi Hanie, Ahmadzade Amiri Ahmad, Veisi Amir
Department of Ophthalmology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Orbit. 2025 Jun;44(3):317-320. doi: 10.1080/01676830.2024.2377248. Epub 2024 Jul 17.
The present study reports a case of solitary neurofibroma attached to the Inferior Rectus (IR) muscle tendon in a 24-year-old healthy woman and reviews the relevant literature regarding the clinical presentation, diagnosis, and management of this uncommon tumor. The patient underwent successful surgical resection of the tumor, leading to the resolution of associated symptoms (left lower eyelid protrusion and redness). Pathological examination confirmed the diagnosis of neurofibroma based on characteristic histopathological and immunohistochemical markers. This case report underscores the rarity of solitary neurofibromas and primary neoplasms of orbit and ocular adnexa. We also discuss the background of solitary neurofibromas originating from orbit and ocular adnexa. The successful management of this case through surgical resection highlights the importance of accurate diagnosis and tailored treatment strategies. To the best of our knowledge, this is the first reported solitary neurofibroma confined solely to the IR tendon.
本研究报告了一例24岁健康女性下直肌肌腱附着处的孤立性神经纤维瘤病例，并回顾了关于这种罕见肿瘤的临床表现、诊断和治疗的相关文献。患者成功接受了肿瘤手术切除，相关症状（左下睑突出和发红）得以缓解。病理检查根据特征性的组织病理学和免疫组化标志物确诊为神经纤维瘤。本病例报告强调了孤立性神经纤维瘤以及眼眶和眼附属器原发性肿瘤的罕见性。我们还讨论了起源于眼眶和眼附属器的孤立性神经纤维瘤的背景。通过手术切除成功治疗该病例凸显了准确诊断和量身定制治疗策略的重要性。据我们所知，这是首例仅局限于下直肌肌腱的孤立性神经纤维瘤报告。
