Hallett J S, Jacobs R L
Ann Allergy. 1985 Oct;55(4):568-70.
Forty-six consecutive patients with a history of recurrent acute bronchitis (chest colds) referred from primary care clinics were studied prospectively to determine if hyperreactive airways (mild bronchial asthma) was a concomitant entity. Mild bronchial asthma was diagnosed in 30/46 (65%) patients by history, physical examination, and routine spirometry, or by methacholine bronchial provocation. The incidence of mild bronchial asthma was markedly increased in patients with a history of recurrent acute bronchitis over that seen in the general population. These results emphasize a need to investigate an underlying cause in patients with recurrent acute bronchitis.
对46例来自基层医疗诊所、有复发性急性支气管炎（感冒引起的咳嗽）病史的患者进行前瞻性研究，以确定气道高反应性（轻度支气管哮喘）是否与之并存。通过病史、体格检查、常规肺功能测定或乙酰甲胆碱支气管激发试验，在46例患者中有30例（65%）被诊断为轻度支气管哮喘。有复发性急性支气管炎病史的患者中，轻度支气管哮喘的发病率明显高于普通人群。这些结果强调了对复发性急性支气管炎患者进行潜在病因调查的必要性。
