Fluoride-Catalyzed Cross-Coupling of Silylamides to CF-Acrylates: Access to Highly Functionalized Trifluoromethylated and Quaternary Fluorinated Molecular Architectures.
作者信息
Bouzbouz Samir
机构信息
CNRS, University of Rouen, INSA of Rouen, COBRA UMR 6014, 1 rue Lucien Tesnière, 76131 Mont Saint Aignan, France.
出版信息
Org Lett. 2024 Jul 26;26(29):6130-6135. doi: 10.1021/acs.orglett.4c01895. Epub 2024 Jul 17.
PMID:39018383
Abstract
A direct and simple catalytic coupling of nonfluorinated and fluorinated silylbutenamides with β-CF α,β-unsaturated esters mediated by fluoride ion was carried out. The transformation proceeded with excellent yields to afford new, highly functionalized trifluoromethylated and quaternary fluorinated products.
摘要
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