Michurina T V, Satdykova G P, Vasil'eva T V, Khrushchov N G
Arkh Anat Gistol Embriol. 1985 Jul;89(7):62-9.
By means of light and electron microscopic methods foci of ectopic hemopoiesis have been investigated. They are formed on acetate-cellulose (AC) membranes implanted into the mice peritoneal cavity and into the mesentery after radiation and intraperitoneal injection of a donor's bone marrow. On the surface of the AC-membranes predominantly granulocytic differentiation of hemopoietic colonies is observed, prevalence of fibroblasts in the sublayer composition, absence of contacts of hemopoietic elements of the colonies with cells of the sublayer. In the mesentery mixed hemopoietic colonies of the donor's origin are revealed consisting of elements of granulocytic, macrophagal and megakaryocytic lines of differentiation. In the mesenteric colonies there are noted mesothelial cells, lipocytes, macrophages, and reticular cells having contacts with hemopoietic cells. The role of the sublayer cells for formation and differentiation of the hemopoietic foci in the experimental systems studied is discussed.
通过光学和电子显微镜方法，对异位造血灶进行了研究。它们形成于植入小鼠腹腔和肠系膜的醋酸纤维素（AC）膜上，这些膜是在辐射和腹腔注射供体骨髓后植入的。在AC膜表面，主要观察到造血集落的粒细胞分化，亚层成分中以成纤维细胞为主，集落的造血成分与亚层细胞无接触。在肠系膜中，发现了供体来源的混合造血集落，由粒细胞、巨噬细胞和巨核细胞分化系的成分组成。在肠系膜集落中，注意到间皮细胞、脂肪细胞、巨噬细胞和网状细胞与造血细胞有接触。讨论了亚层细胞在研究的实验系统中对造血灶形成和分化的作用。
