Prokopchuk V S
Arkh Patol. 1985;47(7):3-10.
Pathomorphism of goiter developing against the background of goiter prevention in the Bukovina endemic area was studied. Subdivision of goiter into endemic and sporadic lost its significance due to the stabilization and levelling of the goiter morbidity. The true (simple or benign) goiter is characterized by an euthyroid course, predominant affection of adult women and domination of the nodular variants. A goiter node is a hyperplastic structural-functional gland unit--the thyron. The leading role in the goiter etiology belongs to endogenous deficiency of thyroid hormones, local factors are significant in the goiter pathogenesis.
对布科维纳地方性甲状腺肿流行区在甲状腺肿预防背景下发生的甲状腺肿病理形态进行了研究。由于甲状腺肿发病率的稳定和趋于平稳,将甲状腺肿分为地方性和散发性已失去意义。真性(单纯性或良性)甲状腺肿的特点是甲状腺功能正常,成年女性受累为主,结节型占主导。甲状腺肿结节是一个增生性结构 - 功能腺单位——甲状腺滤泡。甲状腺激素内源性缺乏在甲状腺肿病因中起主导作用,局部因素在甲状腺肿发病机制中也很重要。