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利用α-淀粉酶仿生绿色合成氧化锌纳米花：从抗菌到毒理学评估

Biomimetic green synthesis of ZnO nanoflowers using α-amylase: from antimicrobial to toxicological evaluation.

作者信息

Mazumder Jahirul Ahmed, Ahmad Atika, Ali Juned, Noori Rubia, Bhuyan Tamanna, Sardar Meryam, Sheehan David

机构信息

Department of Chemistry, Khalifa University of Science and Technology, PO Box 127788, Abu Dhabi, United Arab Emirates.

Department of Biosciences, Jamia Millia Islamia, New Delhi, 110025, India.

出版信息

Sci Rep. 2024 Jul 17;14(1):16566. doi: 10.1038/s41598-024-66140-8.

DOI:10.1038/s41598-024-66140-8
PMID:39019931
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11254910/
Abstract

Biologically mediated synthesis of nanomaterials has emerged as an ecologically benign and biocompatible approach. Our study explores enzymatic synthesis, utilizing α-amylase to synthesize ZnO nanoflowers (ZnO-NFs). X-ray diffraction and energy-dispersive X-ray spectroscopy revealed crystal structure and elemental composition. Dynamic light scattering analysis indicates that ZnO-NFs possess a size of 101 nm. Transmission electron microscopy showed a star-shaped morphology of ZnO-NFs with petal-like structures. ZnO-NFs exhibit potent photocatalytic properties, degrading 90% eosin, 87% methylene blue, and 81% reactive red dyes under UV light, with kinetics fitting the Langmuir-Hinshelwood pseudo-first-order rate law. The impact of pH and interfering substances on dye degradation was explored. ZnO-NFs display efficient bacteriocidal activity against different Gram-positive and negative strains, antibiofilm potential (especially with P. aeruginosa), and hemocompatibility up to 600 ppm, suggesting versatile potential in healthcare and environmental remediation applications.

摘要

生物介导的纳米材料合成已成为一种生态友好且生物相容的方法。我们的研究探索了酶促合成，利用α-淀粉酶合成氧化锌纳米花（ZnO-NFs）。X射线衍射和能量色散X射线光谱揭示了晶体结构和元素组成。动态光散射分析表明ZnO-NFs的尺寸为101纳米。透射电子显微镜显示ZnO-NFs具有花瓣状结构的星形形态。ZnO-NFs表现出强大的光催化性能，在紫外光下可降解90%的曙红、87%的亚甲基蓝和81%的活性红色染料，动力学符合朗缪尔-欣谢尔伍德准一级速率定律。研究了pH值和干扰物质对染料降解的影响。ZnO-NFs对不同的革兰氏阳性和阴性菌株显示出高效的杀菌活性、抗生物膜潜力（尤其是对铜绿假单胞菌）以及高达600 ppm的血液相容性，表明其在医疗保健和环境修复应用中具有多种潜在用途。

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5
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