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绿色合成氧化锌纳米粒子:特性与多方面应用。

Greener Synthesis of Zinc Oxide Nanoparticles: Characterization and Multifaceted Applications.

机构信息

Department of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

King Abdullah Institute of Nanotechnology, King Saud University, Riyadh 11451, Saudi Arabia.

出版信息

Molecules. 2020 Sep 14;25(18):4198. doi: 10.3390/molecules25184198.

Abstract

Nanoparticles (NPs) have unique properties compared to their bulk counterparts, and they have potentials for various applications in many fields of life science. Green-synthesized NPs have garnered considerable interest due to their inherent features such as rapidity, eco-friendliness and cost-effectiveness. Zinc oxide nanoparticles (ZnO NPs) were synthesized using an aqueous extract of as a reducing agent. The resulting nanoparticles were characterized via X-ray diffraction (XRD), dynamic light scattering (DLS), UV-Vis spectroscopy, photoluminescence (PL), transmission electron microscopy (TEM), scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS). The antimicrobial potential of the synthesized ZnO NPs against bacterial and fungal strains was examined by the disk diffusion method, and they showed a promising antibacterial and antifungal potential. The catalytic activity of the synthesized ZnO NPs in reducing methylene blue (MB) and eosin was studied via UV-Vis spectroscopy. The decolorization percentages of the MB and Eosin Y dyes were 84% and 94%, respectively, which indicate an efficient degradation of the ZnO NPs. In addition, the cytotoxic activity of the ZnO NPs on the HeLa cell line was evaluated via in vitro assay. The MTT assay results demonstrate a potent cytotoxic effect of the ZnO NPs against the HeLa cancer cell line.

摘要

纳米粒子(NPs)与它们的块状对应物相比具有独特的性质,并且它们在生命科学的许多领域中具有各种应用的潜力。由于其快速、环保和经济高效等固有特性,绿色合成的 NPs 引起了相当大的兴趣。氧化锌纳米粒子(ZnO NPs)是使用 的水提物作为还原剂合成的。通过 X 射线衍射(XRD)、动态光散射(DLS)、紫外-可见光谱、光致发光(PL)、透射电子显微镜(TEM)、扫描电子显微镜(SEM)和能谱(EDS)对所得纳米粒子进行了表征。通过圆盘扩散法研究了合成的 ZnO NPs 对细菌和真菌菌株的抗菌潜力,结果表明其具有良好的抗菌和抗真菌潜力。通过紫外-可见光谱研究了合成的 ZnO NPs 在还原亚甲基蓝(MB)和曙红中的催化活性。MB 和 Eosin Y 染料的脱色率分别为 84%和 94%,这表明 ZnO NPs 的有效降解。此外,通过体外测定评估了 ZnO NPs 对 HeLa 细胞系的细胞毒性活性。MTT 测定结果表明 ZnO NPs 对 HeLa 癌细胞系具有很强的细胞毒性作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d016/7571220/eae0f2dd981d/molecules-25-04198-g001.jpg

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