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撤回:NCX-4016,一种释放一氧化氮的阿司匹林,通过调节线粒体功能保护内皮细胞免受凋亡。

Retracted: NCX-4016, a nitric oxide-releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function.

出版信息

FASEB J. 2024 Jul 31;38(14):e23834. doi: 10.1096/fsb2.23834.

Abstract

S. Fiorucci, A. Mencarelli, R. Mannucci, E. Distrutti, A. Morelli, P. del Soldato, S. Moncada, "NCX-4016, a nitric oxide-releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function," The FASEB Journal 16, no. 12 (2002): 1645-1647. https://doi.org/10.1096/fj.02-0297fje. The above article, published online on August 07, 2002 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Dr. Loren E. Wold; the Federation of American Societies for Experimental Biology; and Wiley Periodicals LLC. The retraction has been agreed due to concerns raised by a third party regarding the similarity of blots in Figure 7. The authors did not respond to inquiries by either the society or the publisher. In addition, the authors' institution did not respond to our request to begin an investigation. An investigation by the society and the publisher determined that there is overwhelming evidence that images in Figure 7 were manipulated. Because the images in question were imperative to the conclusions presented in the article, all parties agreed the article must be retracted.

摘要

S. 菲奥鲁奇、A. 门卡雷利、R. 曼努奇、E. 迪斯特鲁蒂、A. 莫雷利、P. 德尔索尔达托、S. 蒙卡达,“NCX - 4016,一种释放一氧化氮的阿司匹林,通过调节线粒体功能保护内皮细胞免受凋亡”,《美国实验生物学联合会会刊》第16卷,第12期(2002年):1645 - 1647页。https://doi.org/10.1096/fj.02 - 0297fje。上述文章于2002年8月7日在线发表于威利在线图书馆(wileyonlinelibrary.com),已由该期刊主编洛伦·E. 沃尔德博士、美国实验生物学学会联合会以及威利期刊有限责任公司达成协议予以撤回。撤回是由于第三方对图7中印迹的相似性提出了担忧。作者未回应学会或出版商的询问。此外,作者所在机构也未回应我们开展调查的请求。学会和出版商进行的一项调查确定,有压倒性证据表明图7中的图像被篡改。由于所涉图像对文章中呈现的结论至关重要,各方一致认为该文章必须撤回。

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