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表达关注:糖原合酶激酶 3β(GSK3β)介导 6-羟多巴胺诱导的神经元死亡。

EXPRESSION OF CONCERN: Glycogen synthase kinase 3β (GSK3β) mediates 6-hydroxydopamine-induced neuronal death.

出版信息

FASEB J. 2024 Aug 15;38(15):e23869. doi: 10.1096/fsb2.23869.

DOI:10.1096/fsb2.23869
PMID:39102006
Abstract

G. Chen, K. A. Bower, C. Ma, S. Fang, C. J. Thiele, and J. Luo, "Glycogen Synthase Kinase 3β (GSK3β) Mediates 6-Hydroxydopamine-induced Neuronal Death," The FASEB Journal 18, no. 10 (2004): 1162-1164, https://doi.org/10.1096/fj.04-1551fje. This Expression of Concern for the above article published online on May 07, 2004 in Wiley Online Library (wileyonlinelibrary.com), has been published by agreement between the journal Editor-in-Chief, Loren E. Wold; the Federation of American Societies for Experimental Biology; and Wiley Periodicals LLC. The Expression of Concern has been agreed following concerns raised regarding duplication of the western blot bands presented in Figures 1a and 3a. Further, duplications of bands were also observed within Figure 5c. Due to the length of time that has elapsed since the publication of this article, the original data are no longer available to the authors. The journal has decided to issue an Expression of Concern to inform the readers of these concerns while the authors are repeating the experiments.

摘要

陈刚、鲍尔、马晨、方莎、西里尔·J·泰尔和罗静,“糖原合酶激酶 3β(GSK3β)介导 6-羟多巴胺诱导的神经元死亡”,《美国实验生物学会联合会杂志》18 卷,第 10 期(2004 年):1162-1164,https://doi.org/10.1096/fj.04-1551fje。 该关注声明针对上述于 2004 年 5 月 7 日在线发表在 Wiley Online Library(wileyonlinelibrary.com)上的文章,是在期刊主编 Loren E. Wold、美国实验生物学会联合会、Wiley 期刊有限责任公司三方同意的情况下发表的。该关注声明是基于对图 1a 和图 3a 中出现的 Western blot 条带复制的担忧而达成的。此外,在图 5c 中也观察到条带的复制。由于该文章发表以来已经过去了很长时间,作者无法获得原始数据。期刊决定发布关注声明,以通知读者这些担忧,同时作者正在重复实验。

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