Aishaq Moza, Nafady-Hego Hanaa, Ben Abid Fatma, Al Ajmi Jameela Ali, Hamdi Wedad S, Vinoy Suni, Thomas Anil George, Alrwashdh Saddam, Shaheen Mohamed, Mathew Tintu Elizabeth, Elgendy Mohamed, Joseph Sam, Thomas Christymol, Alex Anju K, Nafady Asmaa, Coyle Peter V, Elgendy Hamed
Hamad Medical Corporation, Doha, Qatar.
Microbiology and Immunology Department, Faculty of Medicine, Assiut University, Assiut, Egypt.
Glob Epidemiol. 2024 Jun 13;8:100149. doi: 10.1016/j.gloepi.2024.100149. eCollection 2024 Dec.
Health care workers (HCWs) may be at a variable risk of SARS-CoV2 infection. Regardless of their involvement in providing direct clinical treatment, most of the prior research had included all HCWs. Understanding infection rates, risk factors and outcomes among different subgroups of HCWs is crucial. From February 28, 2020 to January 1, 2022, we conducted a retrospective analysis encompassing all full-time non-clinical staff (NCS) subcontracted with Hamad Medical Corporation (HMC) facilities. To determine current or previous SARS-CoV2 infection, all personnel underwent RT-PCR and/or serology testing. To identify the demographic factors linked to the risk of infection, we utilized Cox-Hazard regression analysis. Herein 3158/6231 (50.7%) subcontracted NCS tested positive for SARS-CoV-2 by RT-PCR or serology during the research period. The median age was 30 years (IQR 25,35), 69.8% of the population were males, 82.4% were from South Asia, 86.6% did not have any concomitant conditions. 6032 (96.8%) of the population lived in shared housing, while 4749 (76.2%) had low to median levels of education. While infection (PCR positive with or without seropositive results) was independently predicted by male gender, working in the catering, laundry, and security sectors and being intermediate (7-12 years of education), lower (0-6 years of education), higher (exposure to confirmed case), and having symptoms. Male gender, working in the security sectors and being intermediate (7-12 years of education) were independently associated with accidently detected cases (PCR negative and seropositive). 299 (4.8%) required hospitalization, of them 3 cases were severe pneumonia and one required ICU admission without mechanical ventilation, with no deaths reported. In conclusion Infection rates among NCS are high. The majority are asymptomatic and may contribute to ongoing illness spread in the public or in healthcare facilities. During a pandemic, routine screening of this population is crucial and may aid in containing the spread of infection.
医护人员感染新冠病毒的风险可能各不相同。尽管之前的大多数研究将所有医护人员都纳入其中，但无论他们是否参与直接临床治疗。了解不同亚组医护人员的感染率、风险因素和感染后果至关重要。2020年2月28日至2022年1月1日，我们对所有与哈马德医疗公司（HMC）设施签订分包合同的全职非临床工作人员（NCS）进行了回顾性分析。为确定当前或既往的新冠病毒感染情况，所有人员均接受了逆转录聚合酶链反应（RT-PCR）检测和/或血清学检测。为确定与感染风险相关的人口统计学因素，我们采用了Cox风险回归分析。在研究期间，3158/6231（50.7%）的分包非临床工作人员通过RT-PCR或血清学检测新冠病毒呈阳性。中位年龄为30岁（四分位间距25，35），69.8%为男性，82.4%来自南亚，86.6%没有任何合并症。6032（96.8%）的人员居住在合租住房中，而4749（76.2%）的人员教育水平为低至中等。男性、在餐饮、洗衣和安保部门工作、教育程度为中等（7 - 12年教育）、低等（0 - 6年教育）、高等（接触确诊病例）以及有症状是感染（PCR阳性，无论血清学结果是否阳性）的独立预测因素。男性、在安保部门工作以及教育程度为中等（7 - 12年教育）与偶然检测到的病例（PCR阴性且血清学阳性）独立相关。299（4.8%）人需要住院治疗，其中3例为重症肺炎，1例需要入住重症监护病房但无需机械通气，无死亡报告。总之，非临床工作人员的感染率很高。大多数人无症状，可能会导致新冠病毒在公众或医疗机构中持续传播。在疫情期间，对这一人群进行常规筛查至关重要，可能有助于控制感染传播。
