推进精准肿瘤学：对肿瘤微环境和免疫治疗结果的见解。 - Suppr

Advancing precision oncology: Insights into the tumor microenvironment and immunotherapy outcomes.

作者信息

Ugai Tomotaka, Yao Qian, Ugai Satoko, Ogino Shuji

机构信息

Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

出版信息

Innovation (Camb). 2024 Jun 7;5(4):100656. doi: 10.1016/j.xinn.2024.100656. eCollection 2024 Jul 1.

DOI:10.1016/j.xinn.2024.100656

PMID:39021526

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11253650/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7183/11253650/4a12983ecf7f/gr1.jpg

相似文献

Advancing precision oncology: Insights into the tumor microenvironment and immunotherapy outcomes.

Innovation (Camb). 2024 Jun 7;5(4):100656. doi: 10.1016/j.xinn.2024.100656. eCollection 2024 Jul 1.

Extracellular vesicle-based liquid biopsy biomarkers and their application in precision immuno-oncology.

Biomark Res. 2023 Nov 17;11(1):99. doi: 10.1186/s40364-023-00540-2.

Expanding the role of interventional oncology for advancing precision immunotherapy of solid tumors.

Mol Ther Oncolytics. 2021 Dec 21;24:194-204. doi: 10.1016/j.omto.2021.12.018. eCollection 2022 Mar 17.

Unraveling the triad of immunotherapy, tumor microenvironment, and skeletal muscle biomechanics in oncology.

Front Immunol. 2025 Apr 2;16:1572821. doi: 10.3389/fimmu.2025.1572821. eCollection 2025.

Advancing precision medicine: the transformative role of artificial intelligence in immunogenomics, radiomics, and pathomics for biomarker discovery and immunotherapy optimization.

Cancer Biol Med. 2025 Jan 2;22(1):33-47. doi: 10.20892/j.issn.2095-3941.2024.0376.

Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank.

Neuro Oncol. 2021 Mar 25;23(3):356-375. doi: 10.1093/neuonc/noaa277.

Characterizing tumor biology and immune microenvironment in high-grade serous ovarian cancer via single-cell RNA sequencing: insights for targeted and personalized immunotherapy strategies.

Front Immunol. 2025 Jan 17;15:1500153. doi: 10.3389/fimmu.2024.1500153. eCollection 2024.

Integration of graph neural networks and transcriptomics analysis identify key pathways and gene signature for immunotherapy response and prognosis of skin melanoma.

BMC Cancer. 2025 Apr 9;25(1):648. doi: 10.1186/s12885-025-13611-4.

DeepTI: A deep learning-based framework decoding tumor-immune interactions for precision immunotherapy in oncology.

SLAS Discov. 2022 Mar;27(2):121-127. doi: 10.1016/j.slasd.2021.12.003. Epub 2021 Dec 17.

Enhancing Colorectal Cancer Immunotherapy: The Pivotal Role of Ferroptosis in Modulating the Tumor Microenvironment.

Int J Mol Sci. 2024 Aug 23;25(17):9141. doi: 10.3390/ijms25179141.

引用本文的文献

Aptamers Targeting Immune Checkpoints for Tumor Immunotherapy.

Pharmaceutics. 2025 Jul 22;17(8):948. doi: 10.3390/pharmaceutics17080948.

The application of organoids in investigating immune evasion in the microenvironment of gastric cancer and screening novel drug candidates.

Mol Cancer. 2025 Apr 26;24(1):125. doi: 10.1186/s12943-025-02328-4.

Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy.

Adv Sci (Weinh). 2025 Apr;12(14):e2412062. doi: 10.1002/advs.202412062. Epub 2025 Feb 14.

Long-term yogurt intake and colorectal cancer incidence subclassified by abundance in tumor.

Gut Microbes. 2025 Dec;17(1):2452237. doi: 10.1080/19490976.2025.2452237. Epub 2025 Feb 12.

Famitinib plus camrelizumab in patients with advanced colorectal cancer: Data from a multicenter, basket study.

Innovation (Camb). 2025 Jan 6;6(1):100745. doi: 10.1016/j.xinn.2024.100745.

Functionalized biomimetic nanoparticles loaded with salvianolic acid B for synergistic targeted triple-negative breast cancer treatment.

Mater Today Bio. 2025 Jan 1;30:101441. doi: 10.1016/j.mtbio.2024.101441. eCollection 2025 Feb.

本文引用的文献

The Cancer Spectrum Theory.

Cancer Discov. 2024 Apr 4;14(4):589-593. doi: 10.1158/2159-8290.CD-23-1494.

and immunotherapy for gastrointestinal cancer.

Innovation (Camb). 2024 Jan 8;5(2):100561. doi: 10.1016/j.xinn.2023.100561. eCollection 2024 Mar 4.

Is early-onset cancer an emerging global epidemic? Current evidence and future implications.

Nat Rev Clin Oncol. 2022 Oct;19(10):656-673. doi: 10.1038/s41571-022-00672-8. Epub 2022 Sep 6.

Predicting response to immunotherapy in gastric cancer via multi-dimensional analyses of the tumour immune microenvironment.

Nat Commun. 2022 Aug 18;13(1):4851. doi: 10.1038/s41467-022-32570-z.

Cancer as microenvironmental, systemic and environmental diseases: opportunity for transdisciplinary microbiomics science.

Gut. 2022 Jul 12. doi: 10.1136/gutjnl-2022-327209.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Advancing precision oncology: Insights into the tumor microenvironment and immunotherapy outcomes.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

Advancing precision oncology: Insights into the tumor microenvironment and immunotherapy outcomes.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献