• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

拉丁美洲非肌层浸润性膀胱癌管理中的挑战与机遇:来自医疗服务提供者和患者倡导组织的见解

Challenges and opportunities in NMIBC management across Latin America: insights from healthcare providers and a patient advocacy group.

作者信息

McCully Mark, Lipkis Julia, Heller Aryel, Huñis Adrian

机构信息

PharmaValue Partners, 603 Mattison Avenue, Suite 319, Asbury Park, NJ 07712, USA.

A. Hunis & Associates, Oncology Consultants, Hollywood, FL 33019, USA.

出版信息

Ecancermedicalscience. 2024 Jun 7;18:1711. doi: 10.3332/ecancer.2024.1711. eCollection 2024.

DOI:10.3332/ecancer.2024.1711
PMID:39021547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11254412/
Abstract

Non-muscle invasive bladder cancer (NMIBC) is characterised by high rates of recurrence and progression, requiring substantial healthcare resources. In Latin America, the incidence of NMIBC is set to increase due to an aging population and lifestyle changes. To better understand the current challenges for NMIBC treaters and patients, a mixed-methods approach was leveraged combining secondary research with qualitative interviews from healthcare providers in Brazil, Colombia, Mexico and Argentina. Our analysis found that significant challenges persist across the region, particularly due to Calmette-Guérin shortages, inconsistent adherence to clinical guidelines and significant socioeconomic disparities for patients accessing healthcare services. Addressing these challenges requires improved patient advocacy, strategic use of clinical trials and better resource distribution to enhance NMIBC management across Latin America.

摘要

非肌层浸润性膀胱癌(NMIBC)的特点是复发率和进展率高,需要大量医疗资源。在拉丁美洲,由于人口老龄化和生活方式的改变,NMIBC的发病率呈上升趋势。为了更好地了解NMIBC治疗者和患者目前面临的挑战,我们采用了混合方法,将二手研究与来自巴西、哥伦比亚、墨西哥和阿根廷的医疗服务提供者的定性访谈相结合。我们的分析发现,该地区仍然存在重大挑战,特别是由于卡介苗短缺、对临床指南的依从性不一致以及患者获得医疗服务方面存在巨大的社会经济差异。应对这些挑战需要加强患者宣传、战略性地利用临床试验以及更好地分配资源,以加强拉丁美洲对NMIBC的管理。

相似文献

1
Challenges and opportunities in NMIBC management across Latin America: insights from healthcare providers and a patient advocacy group.拉丁美洲非肌层浸润性膀胱癌管理中的挑战与机遇:来自医疗服务提供者和患者倡导组织的见解
Ecancermedicalscience. 2024 Jun 7;18:1711. doi: 10.3332/ecancer.2024.1711. eCollection 2024.
2
Current clinical practice gaps in the treatment of intermediate- and high-risk non-muscle-invasive bladder cancer (NMIBC) with emphasis on the use of bacillus Calmette-Guérin (BCG): results of an international individual patient data survey (IPDS).当前治疗中高危非肌肉浸润性膀胱癌(NMIBC)的临床实践差距,重点是卡介苗(BCG)的使用:国际个体患者数据调查(IPDS)的结果。
BJU Int. 2013 Oct;112(6):742-50. doi: 10.1111/bju.12012. Epub 2013 Mar 1.
3
Oncological Outcomes for Patients with European Association of Urology Very High-risk Non-muscle-Invasive Bladder Cancer Treated with Bacillus Calmette-Guérin or Early Radical Cystectomy.欧洲泌尿外科学会极高危非肌肉浸润性膀胱癌患者行卡介苗或早期根治性膀胱切除术的肿瘤学结局。
Eur Urol Oncol. 2023 Dec;6(6):590-596. doi: 10.1016/j.euo.2023.07.012. Epub 2023 Aug 8.
4
European Association of Urology Guidelines on Non-muscle-invasive Bladder Cancer (TaT1 and Carcinoma In Situ) - 2019 Update.欧洲泌尿外科学会非肌肉浸润性膀胱癌(TaT1 和原位癌)指南 - 2019 年更新版。
Eur Urol. 2019 Nov;76(5):639-657. doi: 10.1016/j.eururo.2019.08.016. Epub 2019 Aug 20.
5
Evaluating the cost-utility of intravesical Bacillus Calmette-Guérin versus radical cystectomy in patients with high-risk non-muscle-invasive bladder cancer in the UK.评估卡介苗膀胱灌注与根治性膀胱切除术对英国高危非肌层浸润性膀胱癌患者的成本效益。
J Med Econ. 2023 Jan-Dec;26(1):411-421. doi: 10.1080/13696998.2023.2189860.
6
CREST: phase III study of sasanlimab and Bacillus Calmette-Guérin for patients with Bacillus Calmette-Guérin-naïve high-risk non-muscle-invasive bladder cancer.CREST 研究:sasanlimab 联合卡介苗治疗卡介苗初治高危非肌层浸润性膀胱癌患者的 III 期临床研究。
Future Oncol. 2024 May;20(14):891-901. doi: 10.2217/fon-2023-0271. Epub 2024 Jan 8.
7
Updated European Association of Urology (EAU) Prognostic Factor Risk Groups Overestimate the Risk of Progression in Patients with Non-muscle-invasive Bladder Cancer Treated with Bacillus Calmette-Guérin.更新后的欧洲泌尿外科协会(EAU)预后因素风险分组高估了接受卡介苗治疗的非肌层浸润性膀胱癌患者的疾病进展风险。
Eur Urol Oncol. 2022 Feb;5(1):84-91. doi: 10.1016/j.euo.2021.11.006. Epub 2021 Dec 15.
8
Reported use of intravesical therapy for non-muscle-invasive bladder cancer (NMIBC): results from the Bladder Cancer Advocacy Network (BCAN) survey.报道的用于非肌肉浸润性膀胱癌(NMIBC)的膀胱内治疗:来自膀胱癌倡导网络(BCAN)调查的结果。
BJU Int. 2012 Oct;110(7):967-72. doi: 10.1111/j.1464-410X.2012.11060.x. Epub 2012 Apr 4.
9
Prognostic Significance of HER2 Expression in Patients with Bacillus Calmette-Guérin-exposed Non-muscle-invasive Bladder Cancer.卡介苗暴露的非肌肉浸润性膀胱癌患者 HER2 表达的预后意义。
Eur Urol Oncol. 2024 Aug;7(4):760-769. doi: 10.1016/j.euo.2023.10.003. Epub 2023 Oct 24.
10
A Multi-Gene Signature of Non-Muscle-Invasive Bladder Cancer Identifies Patients Who Respond to Immunotherapies Including Bacillus Calmette-Guérin and Immune Checkpoint Inhibitors.一种非肌肉浸润性膀胱癌的多基因标志物可识别对包括卡介苗和免疫检查点抑制剂在内的免疫疗法有反应的患者。
Int J Mol Sci. 2024 Mar 28;25(7):3800. doi: 10.3390/ijms25073800.

本文引用的文献

1
Comparison of the Latin America Regulation Landscape and International Reference Health Authorities to Hasten Drug Registration and Clinical Research Applications.比较拉丁美洲监管格局和国际参考卫生当局,以加快药物注册和临床研究申请。
Ther Innov Regul Sci. 2023 Nov;57(6):1287-1297. doi: 10.1007/s43441-023-00565-7. Epub 2023 Sep 8.
2
Intermediate and high-risk non-muscle-invasive bladder cancer: an overview of epidemiology, burden, and unmet needs.中高危非肌层浸润性膀胱癌:流行病学、疾病负担及未满足需求概述
Front Oncol. 2023 Jun 2;13:1170124. doi: 10.3389/fonc.2023.1170124. eCollection 2023.
3
Clinical outcomes in patients with solid tumors living in rural and urban areas followed via telemedicine: experience in a highly complex latin american hospital.远程医疗随访的城乡实体瘤患者的临床结局:一家高度复杂的拉丁美洲医院的经验。
BMC Cancer. 2023 Mar 16;23(1):253. doi: 10.1186/s12885-023-10717-5.
4
Global trends in the epidemiology of bladder cancer: challenges for public health and clinical practice.膀胱癌流行病学的全球趋势:公共卫生和临床实践面临的挑战。
Nat Rev Clin Oncol. 2023 May;20(5):287-304. doi: 10.1038/s41571-023-00744-3. Epub 2023 Mar 13.
5
An updated profile of the cancer burden, patterns and trends in Latin America and the Caribbean.拉丁美洲和加勒比地区癌症负担、模式及趋势的最新概况。
Lancet Reg Health Am. 2022 Sep;13:None. doi: 10.1016/j.lana.2022.100294.
6
Acceptability, appropriateness and feasibility of the Latin American and Caribbean Code against Cancer: perceptions of decision-makers and health professionals in Argentina.《拉丁美洲和加勒比地区抗癌法典》的可接受性、适宜性和可行性:阿根廷决策者和卫生专业人员的看法
Ecancermedicalscience. 2022 Apr 13;16:1375. doi: 10.3332/ecancer.2022.1375. eCollection 2022.
7
Implementation of a molecular tumour board in LATAM: the impact on treatment decisions for patients evaluated at Instituto Alexander Fleming, Argentina.在拉丁美洲实施分子肿瘤学专家组:对在阿根廷亚历山大·弗莱明研究所接受评估的患者治疗决策的影响。
Ecancermedicalscience. 2021 Nov 1;15:1312. doi: 10.3332/ecancer.2021.1312. eCollection 2021.
8
Estimated Costs and Long-term Outcomes of Patients With High-Risk Non-Muscle-Invasive Bladder Cancer Treated With Bacillus Calmette-Guérin in the Veterans Affairs Health System.退伍军人事务部医疗体系中,卡介苗治疗高危非肌肉浸润性膀胱癌患者的预估费用和长期结果。
JAMA Netw Open. 2021 Mar 1;4(3):e213800. doi: 10.1001/jamanetworkopen.2021.3800.
9
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020:全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
10
Increasing costs from bladder cancer in the Brazilian Health System: the role of establishing public health policies.巴西卫生系统中膀胱癌成本的不断增加:制定公共卫生政策的作用。
Int Braz J Urol. 2021 Mar-Apr;47(2):443-447. doi: 10.1590/S1677-5538.IBJU.2020.0658.