Jousset B, Pinaud M, Michel P, Souron R
Cah Anesthesiol. 1985 Jun-Jul;33(4):291-4.
In 100 adult patients undergoing ophthalmic surgery under halothane or enflurane anaesthesia, the electrocardiogram was recorded on magnetic tape and analyzed subsequently for arrhythmias using a high-speed analyzer. Enflurane induced a much less premature atrial contractions (kappa 2 = 4.75; p less than 0.05) and a nodal rhythms (kappa 2 = 4.39; p less than 0.05) than halothane. There were no significant differences between the two drugs in the frequency of premature ventricular contractions and wandering pace maker. Our results confirm those of previous studies during oral surgery that enflurane produced significantly fewer arrhythmias than halothane. The lower incidence of cardiac dysrhythmias and the preservation of cardiovascular stability suggest that enflurane may be the agent of choice for this kind of surgery.
在100例接受氟烷或安氟醚麻醉下眼科手术的成年患者中，心电图被记录在磁带上，随后使用高速分析仪分析心律失常情况。与氟烷相比，安氟醚诱发的房性早搏（卡方值2 = 4.75；p < 0.05）和结性节律（卡方值2 = 4.39；p < 0.05）要少得多。两种药物在室性早搏和游走起搏点的发生频率上没有显著差异。我们的结果证实了先前口腔手术研究的结果，即安氟醚产生的心律失常明显少于氟烷。心律失常发生率较低以及心血管稳定性的维持表明，安氟醚可能是这类手术的首选药物。
