Shamad Mahdi, Al-Mutairi Nawaf
College of Medicine, University of Bahri, Khartoum, SDN.
Faculty of Medicine, Kuwait University, Kuwait City, KWT.
Cureus. 2024 Jul 16;16(7):e64665. doi: 10.7759/cureus.64665. eCollection 2024 Jul.
Cutaneous larva migrans (CLM), caused by third-stage filariform larvae of cat and dog hookworms, presents as pruritic, serpiginous tracks upon skin penetration by larvae from contaminated soil. Herein, we report the successful treatment of two CLM patients using albendazole and ivermectin combination therapy. A 42-year-old man from Kordofan and a 38-year-old man from White Nile State presented with characteristic lesions on their lower extremities, resolving completely within one week post-treatment without recurrence. This report highlights the potential of combined albendazole-ivermectin therapy in managing CLM amid emerging antihelminthic resistance, suggesting that its broader application warrants further investigation.
皮肤幼虫移行症（CLM）由猫和狗钩虫的三期丝状幼虫引起，当幼虫从受污染土壤中穿透皮肤时，会出现瘙痒性、匐行性皮疹。在此，我们报告了使用阿苯达唑和伊维菌素联合疗法成功治疗两名CLM患者的情况。一名来自科尔多凡的42岁男性和一名来自白尼罗州的38岁男性下肢出现典型病变，治疗后一周内完全消退，未复发。本报告强调了在新出现抗蠕虫药耐药性的情况下，阿苯达唑-伊维菌素联合疗法治疗CLM的潜力，表明其更广泛应用值得进一步研究。
