Nagata Mayumi, Matsushima Hiroyuki, Senoo Tadashi
Department of Ophthalmology, Dokkyo Medical University, 880 Kitakobayashi, Mibu City, Tochigi, 321-0293, Japan.
Heliyon. 2024 Jun 14;10(12):e33006. doi: 10.1016/j.heliyon.2024.e33006. eCollection 2024 Jun 30.
We compared the posterior capsule opacification incidences at 5 years postoperatively and the neodymium-yttrium-aluminum-garnet capsulotomy rates at 10 years postoperatively for two types of intraocular lenses with different optical properties and shapes. This randomized, controlled, prospective, single-blinded study with intra-individual comparisons was conducted between July 21, 2009, and August 31, 2011, at the Dokkyo Medical University Hospital, Tochigi, Japan. Thirty patients (60 eyes) underwent bilateral cataract surgery and received a XY1 intraocular lens in one eye and a FY-60AD intraocular lens in the other. Both intraocular lenses are acrylic and manufactured by HOYA. The XY1 lens is a single-piece, tinted intraocular lens featuring an ultraviolet/ozone treatment on the posterior surface of the lens optic, aimed at enhancing posterior capsule adhesion to prevent posterior capsule opacification. Conversely, the FY-60AD is a tinted intraocular lens with modified polymethylmethacrylate C-loops and no ultraviolet/ozone treatment of the optic. Scheimpflug images were taken using EAS-1000 (NIDEK Co., Ltd., Aichi, Japan), and the scattered light intensity (computer compatible tape) on the posterior surface of the intraocular lens was calculated and evaluated as the posterior capsule opacification. The scattered light values of the XY1 and FY-60AD groups were 6.50 ± 5.69 and 11.64 ± 5.30 computer compatible tape, respectively, at 5 years postoperatively. The cumulative survival incidence after neodymium-yttrium-aluminum-garnet laser capsulotomy was 74.8 % in the XY1 group and 13.8 % in the FY-60AD group at 10 years postoperatively. The surface-modified intraocular lens XY1 reduced the incidence of posterior capsule opacification even 10 years after surgery. Surface modification to increase the adhesion between the intraocular lens and the capsule effectively prevents posterior capsule opacification.
我们比较了两种具有不同光学特性和形状的人工晶状体术后5年的后囊膜混浊发生率以及术后10年的钕钇铝石榴石囊膜切开率。这项具有个体内比较的随机、对照、前瞻性、单盲研究于2009年7月21日至2011年8月31日在日本枥木县的独协医科大学医院进行。30例患者（60只眼）接受了双侧白内障手术，一只眼植入XY1人工晶状体，另一只眼植入FY - 60AD人工晶状体。两种人工晶状体均为丙烯酸材质，由豪雅公司生产。XY1晶状体是一体式、带色人工晶状体，其晶状体光学部后表面经过紫外线/臭氧处理，目的是增强后囊膜粘连以防止后囊膜混浊。相反，FY - 60AD是一种带色人工晶状体，具有改良的聚甲基丙烯酸甲酯C袢，且光学部未经过紫外线/臭氧处理。使用EAS - 1000（日本爱知县尼德克株式会社）拍摄Scheimpflug图像，并计算和评估人工晶状体后表面的散射光强度（计算机兼容磁带）作为后囊膜混浊情况。术后5年，XY1组和FY - 60AD组的散射光值分别为6.50±5.69和11.64±5.30计算机兼容磁带。术后10年，XY1组钕钇铝石榴石激光囊膜切开术后的累积生存发生率为74.8%，FY - 60AD组为13.8%。表面改性的人工晶状体XY1即使在术后10年也降低了后囊膜混浊的发生率。增加人工晶状体与囊膜之间粘连的表面改性可有效防止后囊膜混浊。
