Shi Yaping, Liu Jian, Wang Ruikang K
Department of Bioengineering, University of Washington, Seattle, WA, USA.
Department of Ophthalmology, University of Washington, Seattle, WA, USA.
Biomed Opt Express. 2024 Jun 27;15(7):4365-4380. doi: 10.1364/BOE.528287. eCollection 2024 Jul 1.
We report a high-speed, long-range, and wide-field swept-source optical coherence tomography (SS-OCT) system aimed for imaging microstructures and microcirculations in the oral cavity. This system operates at a scan speed of 600 kHz, delivering a wide imaging field of view at 42 × 42 mm and a ranging distance of 36 mm. To simultaneously meet the requirements of high speed and long range, it is necessary for the k-clock trigger signal to be generated at its maximum speed, which may induce non-linear phase response in electronic devices due to the excessive k-clock frequency bandwidth, leading to phase errors. To address this challenge, we introduced a concept of electrical dispersion and a global k-clock compensation approach to improve overall performance of the imaging system. Additionally, image distortion in the wide-field imaging mode is also corrected using a method based on distortion vector maps. With this system, we demonstrate comprehensive structural and blood flow imaging of the anterior oral cavity in healthy individuals. The high-speed, long-range, and wide-field SS-OCT system opens new opportunities for comprehensive oral cavity examinations and holds promise as a reliable tool for assessing oral health conditions.
我们报道了一种高速、远程和宽视野扫频光学相干断层扫描（SS-OCT）系统，旨在对口腔中的微观结构和微循环进行成像。该系统以600 kHz的扫描速度运行，提供42×42 mm的宽成像视野和36 mm的测距范围。为了同时满足高速和远程的要求，k时钟触发信号必须以其最大速度生成，这可能会由于k时钟频率带宽过大而在电子设备中引起非线性相位响应，从而导致相位误差。为了应对这一挑战，我们引入了电色散的概念和全局k时钟补偿方法来提高成像系统的整体性能。此外，还使用基于畸变矢量图的方法校正宽视野成像模式下的图像畸变。利用该系统，我们展示了健康个体口腔前部的综合结构和血流成像。这种高速、远程和宽视野的SS-OCT系统为全面的口腔检查开辟了新的机会，并有望成为评估口腔健康状况的可靠工具。
