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MRI 证实的镰状细胞病患者耳蜗动脉梗死:病例报告。

MRI-confirmed cochlear artery infarct clinically diagnosed in a patient with sickle cell disease: a case report.

机构信息

Department of Otology and Neurotology, CHU Lille, Lille, F-59000, France.

Department of Otology and Neurotology, Hôpital Roger Salengro, University Hospital of Lille (CHU Lille), rue Emile Laine, Lille cedex, 59037, France.

出版信息

Eur Arch Otorhinolaryngol. 2024 Dec;281(12):6699-6703. doi: 10.1007/s00405-024-08837-0. Epub 2024 Jul 18.

DOI:10.1007/s00405-024-08837-0
PMID:39025977
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11564269/
Abstract

PURPOSE

To corroborate the vascular etiology of sudden sensorineural hearing loss (SNHL) utilizing magnetic resonance imaging (MRI).

PATIENT

A 24-year-old male with a history of sickle cell disease experienced sudden SNHL and right horizontal nystagmus, without accompanying vertigo.

INTERVENTION

Audiometric evaluation revealed left-sided SNHL, predominantly affecting high frequencies. Video head impulse testing demonstrated isolated dysfunction of the left posterior semicircular canal. An urgent brain MRI identified a recent punctiform ischemic stroke in the frontal region. A subsequent MRI, conducted with a 4-hour delay and post-contrast enhancement, highlighted a hyperintense signal within the left cochlear region and the left posterior semicircular canal.

CONCLUSION

The investigative results substantiate an infarction in the territory of the cochlear artery, precipitated by a vaso-occlusive event, thereby reinforcing the vascular hypothesis of cochleovestibular artery syndrome. This case underscores the congruence between clinical observations and delayed post-contrast MRI findings.

摘要

目的

利用磁共振成像(MRI)证实突发性聋(SNHL)的血管病因。

患者

一名 24 岁男性,有镰状细胞病史,出现突发性 SNHL 和右侧水平性眼球震颤,但无伴随眩晕。

干预措施

听力评估显示左侧 SNHL,主要影响高频。视频头脉冲测试显示左侧后半规管孤立性功能障碍。紧急脑部 MRI 发现额区近期点状缺血性中风。随后进行的 MRI,在 4 小时延迟和增强后,显示左侧耳蜗区和左侧后半规管内呈高信号。

结论

研究结果证实,由于血管阻塞事件导致耳蜗动脉供血区梗死,从而支持耳蜗前庭动脉综合征的血管假说。该病例突出了临床观察结果与延迟后增强 MRI 发现之间的一致性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/11564269/ca72aa1c72aa/405_2024_8837_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/11564269/23ecbb4fd0fd/405_2024_8837_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/11564269/880d8f61c0df/405_2024_8837_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/11564269/ff5628c3f833/405_2024_8837_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/11564269/ca72aa1c72aa/405_2024_8837_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/11564269/23ecbb4fd0fd/405_2024_8837_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/11564269/880d8f61c0df/405_2024_8837_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/11564269/ff5628c3f833/405_2024_8837_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd0b/11564269/ca72aa1c72aa/405_2024_8837_Fig4_HTML.jpg

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