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急诊中线剖腹术后发生腹部爆裂的临床后果:一项前瞻性观察性队列研究。

The clinical consequences of burst abdomen after emergency midline laparotomy: a prospective, observational cohort study.

机构信息

Department of Gastrointestinal and Hepatic Diseases, Copenhagen University Hospital - Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.

Emergency Surgery Research Group Copenhagen (EMERGE Cph), Copenhagen University Hospital - Herlev and Gentofte Herlev, Herlev, Denmark.

出版信息

Hernia. 2024 Oct;28(5):1861-1870. doi: 10.1007/s10029-024-03104-x. Epub 2024 Jul 20.

Abstract

PURPOSE

The emergency midline laparotomy is a commonly performed procedure with a burst abdomen being a critical surgical complication requiring further emergency surgery. This study aimed to investigate the clinical outcomes of patients with burst abdomen after emergency midline laparotomy.

METHODS

A single-center, prospective, observational cohort study of patients undergoing emergency midline laparotomy during a two-year period was done. Abdominal wall closure followed a standardized technique using monofilament, slowly absorbable suture in a continuous suturing technique with a suture-to-wound ratio of at least 4:1. Treatment of burst abdomen was surgical. Data, including intra-hospital postoperative complications, were collected and registered chronologically based on journal entries. The primary outcome was to describe postoperative complications, length of stay, and the overall morbidity based on the Comprehensive Complication Index (CCI), stratified between patients who did and did not suffer from a burst abdomen during admission.

RESULTS

A total of 543 patients were included in the final cohort, including 24 patients with burst abdomen during admission. The incidence of burst abdomen after emergency midline laparotomy was 4.4%. Patients with a burst abdomen had a higher total amount of complications per patient (median of 3, IQR 1.3-5.8 vs. median of 1, IQR 0.0-3.0; p = 0.001) and a significantly higher CCI (median of 53.0, IQR 40.3-94.8 vs. median of 21.0, IQR 0.0-42.0; p =  < 0.001).

CONCLUSION

Patients with burst abdomen had an increased risk of postoperative complications during admission as well as a longer and more complicated admission with multiple non-surgical complications.

摘要

目的

急诊中线剖腹术是一种常见的手术,而腹部破裂是一种严重的手术并发症,需要进一步进行紧急手术。本研究旨在探讨急诊中线剖腹术后发生腹部破裂患者的临床结局。

方法

对两年期间行急诊中线剖腹术的患者进行单中心、前瞻性、观察性队列研究。腹壁闭合采用单丝、可缓慢吸收缝线,连续缝合技术,缝线与伤口比至少为 4:1。腹部破裂的治疗采用手术方法。收集并按时间顺序登记包括院内术后并发症在内的数据。主要结局是描述术后并发症、住院时间和基于综合并发症指数(CCI)的总发病率,按入院期间是否发生腹部破裂分层。

结果

最终队列共纳入 543 例患者,其中 24 例患者在入院期间发生腹部破裂。急诊中线剖腹术后腹部破裂的发生率为 4.4%。发生腹部破裂的患者每位患者的总并发症数量更高(中位数 3,IQR 1.3-5.8 比中位数 1,IQR 0.0-3.0;p=0.001),CCI 显著更高(中位数 53.0,IQR 40.3-94.8 比中位数 21.0,IQR 0.0-42.0;p<0.001)。

结论

腹部破裂患者在入院期间发生术后并发症的风险增加,且住院时间更长,更复杂,伴有多种非手术并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f717/11449993/b169620526e2/10029_2024_3104_Fig1_HTML.jpg

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