Eldridge M W, Berman W, Greene E R
J Ultrasound Med. 1985 Sep;4(9):453-8. doi: 10.7863/jum.1985.4.9.453.
An echo-Doppler duplex scanner (DS) was used to make serial noninvasive measurements of human fetal abdominal aortic blood flow (Q). In 18 uncomplicated pregnancies (16 weeks to term), Doppler shifted frequency spectral waveforms (delta f), Doppler incident angles (theta), and peak systolic lumen diameters (D) were measured. Using the measured values of delta f and theta, the temporal average blood velocity (V) in the cardiac cycle was calculated from the Doppler equation. Values of Q were calculated using the equation: Q = pi X (D2/2) X V X HR, where HR is the heart rate. Gestational age (GA) and fetal weight (FW) were estimated from biparietal and transverse abdominal diameters. Each fetus was studied three to eight times at 2- to 4-week intervals. Results showed that Q increased nonlinearly with GA. Normalized to estimated FW, values of Q/kg did not vary significantly with estimated GA and gave an overall mean value (+/- standard deviation) during gestation of 184 +/- 35 ml/kg/min.
使用回声多普勒双功能扫描仪（DS）对人类胎儿腹主动脉血流（Q）进行系列无创测量。在18例无并发症的妊娠（孕16周直至足月）中，测量了多普勒频移频谱波形（δf）、多普勒入射角（θ）和收缩期峰值管腔直径（D）。利用测得的δf和θ值，根据多普勒方程计算心动周期中的时间平均血流速度（V）。Q值使用以下公式计算：Q = π×（D²/2）×V×HR，其中HR为心率。根据双顶径和腹横径估算胎龄（GA）和胎儿体重（FW）。每隔2至4周对每个胎儿进行3至8次研究。结果显示，Q随GA呈非线性增加。以估算的FW进行标准化后，Q/kg值随估算的GA变化不显著，孕期总体平均值（±标准差）为184±35 ml/kg/min。
