Department of Oral Health Promotion, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Cancer Control Center, Osaka International Cancer Institute, Osaka, Japan.
Community Dent Oral Epidemiol. 2024 Dec;52(6):911-918. doi: 10.1111/cdoe.12997. Epub 2024 Jul 19.
Utility values enable relative comparisons across various health conditions, providing information for efficient allocation of healthcare resources. This study aimed to (1) quantify the utility values attributable to oral health-related quality of life (OHRQoL) in Japanese adults and (2) develop models for converting the 14-item Oral Health Impact Profile (OHIP-14) scores into EuroQoL 5-dimension 5-level (EQ-5D-5L)-based utility values.
This was a cross-sectional study. Data from a large-scale Internet survey of Japanese adults conducted in 2022 (n = 28 405; mean age 48.2 years) were analysed. Multiple linear regression models were fitted to investigate the association between OHIP-14 scores and EQ-5D-5L-based utility values, adjusting for confounders. Conversion models were developed using a random half of the participants, and the observed and predicted utility values in the other half were compared to evaluate the model performance.
Among the participants, 55.2% scored 0, 20.9% scored 1-5 and 23.9% scored 6-56 on the OHIP-14, corresponding mean utility values of 0.93, 0.90 and 0.84, respectively. A one-point increase in the OHIP-14 score was associated with a lower utility value (coefficient: -0.0053; 95% confidence interval:health-related quality of life -0.0056, -0.0051). The estimated utility value attributable to OHIP-14 was -23.3 per 1000 individuals, greater than that for other prevalent chronic conditions, including hypertension and diabetes (-2.9 and -7.1 per 1000 individuals, respectively). The conversion model incorporated the OHIP-14 total score, age, sex and self-rated health, predicted utility scores on average and captured differences according to the number of teeth lost. However, there was a discrepancy between predicted and observed utility values in the lower utility value groups.
OHRQoL substantially impacted utility values at the population level. The OHIP-14 holds the potential as a valuable tool for predicting average utility values based on oral health conditions; however, the prediction performance was relatively low for individuals with a lower health-related quality of life.
效用值可用于比较各种健康状况，为有效分配医疗保健资源提供信息。本研究旨在：(1) 量化日本成年人口腔健康相关生活质量（OHRQoL）的效用值；(2) 建立将 14 项口腔健康影响量表（OHIP-14）评分转换为 EuroQoL 五维 5 级（EQ-5D-5L）效用值的模型。
这是一项横断面研究。对 2022 年进行的一项日本成年人大规模互联网调查（n=28405；平均年龄 48.2 岁）的数据进行了分析。使用多元线性回归模型来研究 OHIP-14 评分与 EQ-5D-5L 效用值之间的关联，同时调整混杂因素。使用参与者的一半数据建立转换模型，并比较另一半的观察值和预测值的效用值，以评估模型性能。
在参与者中，55.2%的 OHIP-14 得分为 0，20.9%的得分为 1-5，23.9%的得分为 6-56，相应的平均效用值分别为 0.93、0.90 和 0.84。OHIP-14 评分每增加 1 分，效用值越低（系数：-0.0053；95%置信区间：-0.0056，-0.0051）。OHIP-14 导致的估计效用值为-23.3 每 1000 人，高于其他常见慢性疾病（高血压和糖尿病每 1000 人分别为-2.9 和-7.1）。转换模型纳入了 OHIP-14 总分、年龄、性别和自我报告的健康状况，平均预测了效用得分，并根据失牙数量捕捉了差异。然而，在效用值较低的组中，预测值和观察值之间存在差异。
口腔健康相关生活质量在人群水平上对效用值有重大影响。OHIP-14 有可能成为一种有价值的工具，用于根据口腔健康状况预测平均效用值；然而，对于生活质量较低的个体，预测性能相对较低。
