Pu YangPeng, Feng YouGang, Zhao WenCai
School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Sichuan Province, Suining Central Hospital, Suining, China.
Neurourol Urodyn. 2024 Nov;43(8):2030-2038. doi: 10.1002/nau.25552. Epub 2024 Jul 20.
This investigation seeks to determine the triglyceride glucose (TyG) index's link to stress urinary incontinence (SUI) in American females of adult age.
The investigation relied on data acquired via the National Health and Nutrition Examination Survey (NHANES) conducted over the period from 2011 to 2018. The independent relationship between TyG index and SUI was tested using multivariate logistic regression analysis. We applied a smooth curve fitting approach to analyze the interrelation of them. In addition, subgroup analysis was conducted and interaction experiments were conducted.
Among 4459 female participants aged 20 and above, TyG index and SUI demonstrated a favorable correlation. Model 3 indicated that with every single-unit rise in the TyG index, the incidence of SUI increases by 18% [1.18 (1.01, 1.38)]. In contrast to individuals in the lowest tertile, subjects within the highest tertile of the TyG index exhibited a 68% increase in SUI incidence [1.68 (95% CI: 1.26, 2.23), 0.0004]. By using smooth curve fitting, a nonlinear positive evidence of an interconnection of the TyG index to SUI was identified.
Women exhibiting increased TyG index levels are at a heightened risk of SUI. TyG index displays a stronger correlation than that observed with BMI. According to our findings, the TyG index is viewed as a potential tool for identifying SUI in women, and monitoring the value of TyG index may be helpful for predicting the occurrence of SUI.
本研究旨在确定甘油三酯葡萄糖（TyG）指数与美国成年女性压力性尿失禁（SUI）之间的联系。
该研究依赖于2011年至2018年期间通过美国国家健康与营养检查调查（NHANES）获得的数据。使用多变量逻辑回归分析来测试TyG指数与SUI之间的独立关系。我们采用平滑曲线拟合方法来分析它们之间的相互关系。此外，还进行了亚组分析和交互实验。
在4459名年龄在20岁及以上的女性参与者中，TyG指数与SUI呈现出显著的相关性。模型3表明，TyG指数每上升一个单位，SUI的发病率就会增加18%[1.18（1.01，1.38）]。与TyG指数最低三分位数的个体相比，TyG指数最高三分位数的个体SUI发病率增加了68%[1.68（95%CI：1.26，2.23），P=0.0004]。通过平滑曲线拟合，发现TyG指数与SUI之间存在非线性正相关的证据。
TyG指数升高的女性患SUI的风险更高。TyG指数显示出比体重指数（BMI）更强的相关性。根据我们的研究结果，TyG指数被视为识别女性SUI的潜在工具，监测TyG指数的值可能有助于预测SUI的发生。
