Bahrami Fereshteh, Eftekhar Maryam, Tabibnejad Nasim
Research and Clinical Centre for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Research and Clinical Centre for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Email:
Int J Fertil Steril. 2024 Jul 13;18(Suppl 1):17-21. doi: 10.22074/ijfs.2023.2000790.1460.
Embryo transfer (ET) is an important step in assisted reproductive technology. Uterine length measurement before ET (ULMbET) enables the determination of catheter length and anatomical variation before the ET. Therefore, in this study, we aim to compare ULMbET and transabdominal ultrasound-guided ET (TAUGET).
This open-label randomised clinical trial enrolled 264 women who were scheduled for frozen- thawed ET (FET) cycles. The women were randomised to the ULMbET or TAUGET group for ET. The primary outcome of this study was clinical pregnancy.
A total of 132 women were randomly assigned to the ULMbET group and 132 women to the TAUGET group. However, four women in the ULMbET group did not receive the allocated method after randomisation. Finally, 128 women from the ULMbET group and 132 women from the TAUGET group were assessed. No statistically significant differences existed in chemical pregnancy rate (31.3 vs. 36.4%, P=0.384), clinical pregnancy rate (23.4 vs. 28%, P=0.397), and implantation rate (15 vs. 17.8%, P=0.401) between the ULMbET and TAUGET groups, respectively.
The results of this clinical trial show no differences in pregnancy outcomes in FET cycles following ULMbET and TAUGET (registration number: IRCT20110509006420N240).
胚胎移植（ET）是辅助生殖技术中的重要一步。胚胎移植前测量子宫长度（ULMbET）有助于在胚胎移植前确定导管长度和解剖变异情况。因此，在本研究中，我们旨在比较ULMbET和经腹超声引导下胚胎移植（TAUGET）。
这项开放标签随机临床试验纳入了264名计划进行冻融胚胎移植（FET）周期的女性。这些女性被随机分为ULMbET组或TAUGET组进行胚胎移植。本研究的主要结局是临床妊娠。
共有132名女性被随机分配到ULMbET组，132名女性被分配到TAUGET组。然而，ULMbET组中有4名女性在随机分组后未接受分配的方法。最终，对ULMbET组的128名女性和TAUGET组的132名女性进行了评估。ULMbET组和TAUGET组之间的化学妊娠率（31.3%对36.4%，P = 0.384）、临床妊娠率（23.4%对28%，P = 0.397）和着床率（15%对17.8%，P = 0.401）分别无统计学显著差异。
这项临床试验的结果表明，ULMbET和TAUGET后FET周期的妊娠结局无差异（注册号：IRCT20110509006420N240）。
