Romero-Arias Tatiana, Hernández-Velasco Rocío, Betancort Moisés, Mena-Chamorro Patricio, Sabater Gálvez Lucía, Pérez Del Olmo Adrián
Facultad de Ciencias de la Salud, Universidad Europea de Canarias, Santa Cruz, Spain.
Departamento de Psicología Cognitiva, Social y Organizacional, Universidad de La Laguna, San Cristóbal de La Laguna, Spain.
Folia Phoniatr Logop. 2025;77(2):147-160. doi: 10.1159/000540457. Epub 2024 Jul 19.
The predominant alterations in voice of patients with multiple sclerosis (MS) are phonatory instability, vocal asthenia and roughness, shortness of breath, hypophonia, and hypernasality. However, research on alterations of acoustic parameters has few studies and disparate results. The objective of this study was to investigate voice disturbances in patients with MS, both with objective measures (analysis of biomechanical) and subjective measures (scales and questionnaires).
This is an experimental study with a total of 20 participants with MS. Voice samples were collected, and biomechanical correlates were analyzed through the Clinical Voice Systems program, Online Lab App. The VHI-30 (Voice Handicap Index) questionnaire, the GRBAS (grade, roughness, breathiness, asthenia, strain) scale, and the Hospital Anxiety and Depression Scale were used as subjective measures.
Ninety-five percentages of participants feel and describe dysphonic difficulties. Self-perception of vocal disability correlated with auditory vocal perceptual analysis in the sample of women.
The biomechanical parameters showed alterations in the strength of the glottic closure, the efficiency index, and the structural imbalance index.
多发性硬化症（MS）患者声音的主要改变有声带发声不稳定、发声无力、声音粗糙、呼吸急促、发声减弱和鼻音过重。然而，关于声学参数改变的研究较少且结果不一。本研究的目的是通过客观测量（生物力学分析）和主观测量（量表和问卷）来调查MS患者的声音障碍。
这是一项实验研究，共有20名MS患者参与。收集声音样本，并通过临床语音系统程序（在线实验室应用程序）分析生物力学相关性。使用VHI-30（嗓音障碍指数）问卷、GRBAS（分级、粗糙、呼吸音、无力、紧张）量表和医院焦虑抑郁量表作为主观测量工具。
95%的参与者感觉并描述了发声困难。在女性样本中，嗓音残疾的自我认知与听觉嗓音感知分析相关。
生物力学参数显示声门闭合强度、效率指数和结构失衡指数存在改变。
