Muscat Neil, Gupta Apurv, Arifuzaman Mohammed, Soxibova Firuza
General Surgery, Bolton NHS Foundation Trust, Bolton, GBR.
General Surgery, North Manchester General Hospital, Manchester, GBR.
Cureus. 2024 Jun 21;16(6):e62807. doi: 10.7759/cureus.62807. eCollection 2024 Jun.
Pilonidal sinus disease (PSD) is a common condition associated with significant morbidity and healthcare costs. High recurrence rates still pose a considerable challenge in managing PSD, with no universally accepted guideline in place to guide management. Laser hair epilation offers a way to reduce recurrence rates with reports within the current literature demonstrating positive outcomes compared to alternative approaches. This review was conducted by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement standards. The primary outcome measure was the recurrence rate of PSD at a minimum of one year following laser hair epilation. The electronic databases of MEDLINE, EMBASE, CINAHL, Google Scholar, PubMed, and Cochrane Central Register of Controlled Trials (CENTRAL) were searched. OpenMeta Analyst (Brown University School of Public Health, Providence, RI) software was used for data synthesis. Three randomized controlled trials met the inclusion criteria with laser hair epilation treatments offering a significant reduction in PSD recurrence rates on odds ratio analysis: 0.319 ( 0.160, 0.636), -value = 0.0001. Secondary outcomes involving patient disability days, caregiver disability days, health-related quality-of-life (HRQOL) scores, healthcare satisfaction scores, and perceived stigma were discussed qualitatively. The authors offer a decisive recommendation in favor of laser hair epilation in PSD; however, they recommend further high-quality trials to investigate the ideal timing and frequency of laser hair epilation sessions.
藏毛窦疾病（PSD）是一种常见疾病，会导致严重的发病率和医疗费用。高复发率在PSD的治疗中仍然是一个相当大的挑战，目前尚无普遍接受的指南来指导治疗。激光脱毛提供了一种降低复发率的方法，当前文献中的报告表明，与其他方法相比，其效果良好。本综述按照系统评价和Meta分析的首选报告项目（PRISMA）声明标准进行。主要结局指标是激光脱毛后至少一年的PSD复发率。检索了MEDLINE、EMBASE、CINAHL、谷歌学术、PubMed和Cochrane对照试验中央注册库（CENTRAL）的电子数据库。使用OpenMeta Analyst（布朗大学公共卫生学院，普罗维登斯，罗德岛）软件进行数据合成。三项随机对照试验符合纳入标准，经比值比分析，激光脱毛治疗可显著降低PSD复发率：0.319（0.160，0.636），P值=0.0001。对涉及患者残疾天数、护理人员残疾天数、健康相关生活质量（HRQOL）评分、医疗满意度评分和感知耻辱感的次要结局进行了定性讨论。作者果断推荐在PSD中使用激光脱毛；然而，他们建议进一步开展高质量试验，以研究激光脱毛疗程的理想时机和频率。
