Pan Tengwei, Wang Shanshan
Neurology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, CHN.
Cureus. 2024 Jun 19;16(6):e62687. doi: 10.7759/cureus.62687. eCollection 2024 Jun.
Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare and fatal neurodegenerative disorder belonging to a group of diseases known as prion disease. Characterized by the formation of abnormal prion proteins in the brain, these conditions lead to tissue damage and vacuolation, giving the brain a sponge-like appearance. sCJD represents the most prevalent form of CJD, accounting for roughly 85% of all CJD cases. We report a case with unusual clinical manifestations. The patient experienced progressive neurological symptoms and MRI progression.
散发性克雅氏病（sCJD）是一种罕见的致命性神经退行性疾病，属于一组被称为朊病毒病的疾病。其特征是大脑中形成异常的朊病毒蛋白，这些情况会导致组织损伤和空泡化，使大脑呈现出海绵状外观。sCJD是克雅氏病最常见的形式，约占所有克雅氏病病例的85%。我们报告了一例具有不寻常临床表现的病例。该患者出现进行性神经症状和MRI进展。
