Freij B J, Gessouroun M, Fixler D E, Fink C W
Pediatr Cardiol. 1985;6(2):95-8. doi: 10.1007/BF02282745.
A fatal case of Kawasaki disease with extensive cardiac involvement in an 11-week-old boy is described. Two-dimensional echocardiography revealed enlargement of the left ventricle, left atrium, and aortic root as well as dilatation of the left main coronary artery. Cardiac catheterization revealed both aortic and mitral regurgitation and fusiform dilatation of the proximal segments of the coronary arteries. The clinical course was characterized by multisystem failure and death on day 31 of the illness. Aortic regurgitation is a very rare complication of Kawasaki disease and has been previously reported in one Japanese infant. The pathogenesis of aortic regurgitation in this disease is not known but may be due to aortitis and/or valvulitis. Kawasaki disease should be included as a cause of aortic regurgitation in infants.
本文描述了一名11周大男婴患川崎病并伴有广泛心脏受累的致命病例。二维超声心动图显示左心室、左心房和主动脉根部增大，以及左主冠状动脉扩张。心导管检查显示主动脉瓣和二尖瓣反流，以及冠状动脉近端节段的梭形扩张。临床病程的特征是多系统功能衰竭，并于患病第31天死亡。主动脉瓣反流是川崎病非常罕见的并发症，此前在一名日本婴儿中曾有报道。该病中主动脉瓣反流的发病机制尚不清楚，但可能是由于主动脉炎和/或瓣膜炎。川崎病应被列为婴儿主动脉瓣反流的病因之一。
