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玻璃体内注射地塞米松植入剂(Ozurdex)治疗眼部弓蛔虫病

Intravitreal Dexamethasone Implant (Ozurdex) for Ocular Toxocariasis.

作者信息

Zhou Yongwei, Zhen Fangyuan, Wu Jiahui, Wang Shasha, Lu Xiaoyan, Yang Ge, Hu Zhirou, Chen Fei, Li Qiuming, Dong Shuqian

机构信息

Department of Ophthalmology The First Affiliated Hospital of Zhengzhou University Henan Provincial Ophthalmic Hospital, Zhengzhou, China.

出版信息

J Ophthalmol. 2024 Jul 15;2024:6685092. doi: 10.1155/2024/6685092. eCollection 2024.

Abstract

This study aimed to evaluate the efficacy and safety of intravitreal dexamethasone implants in the treatment of ocular toxocariasis (OT). A retrospective analysis was performed on 6 cases in which laboratory tests diagnosed OT. All patients were administered with intravitreal dexamethasone implants with or without vitrectomy. The average follow-up time was 19.7 months. All operated eyes achieved anatomic success, and all patients' visual acuity was improved. Five of these six had a visual acuity of 20/100, and three had final acuity of 20/40 or even better. Intravitreal dexamethasone implants can be used to treat different types of OT, which not only effectively control inflammation and improve the patient's vision but also reduce the use of systemic glucocorticoids.

摘要

本研究旨在评估玻璃体内注射地塞米松植入物治疗眼弓蛔虫病(OT)的疗效和安全性。对6例经实验室检查确诊为OT的患者进行了回顾性分析。所有患者均接受了玻璃体内注射地塞米松植入物,部分患者同时接受了玻璃体切除术。平均随访时间为19.7个月。所有手术眼均获得解剖学上的成功,所有患者的视力均得到改善。这6例患者中有5例视力达到20/100,3例最终视力达到20/40或更好。玻璃体内注射地塞米松植入物可用于治疗不同类型的OT,不仅能有效控制炎症、改善患者视力,还能减少全身糖皮质激素的使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0c6/11262872/6a6a4c4bd301/JOPH2024-6685092.001.jpg

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