Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, USA.
Division of Biology & Biological Engineering, California Institute of Technology, Pasadena, California, USA.
Clin Infect Dis. 2024 Oct 15;79(4):815-818. doi: 10.1093/cid/ciae381.
Early detection of severe acute respiratory syndrome coronavirus 2 infection by diagnostic tests can prompt actions to reduce transmission and improve treatment efficacy, especially for vulnerable groups such as immunocompromised individuals. Recent evidence suggests that sampling the throat in addition to the nose improves clinical sensitivity during early infection for both antigen and molecular coronavirus disease 2019 tests. We urge test manufacturers to validate tests for use with throat swab, in combination with nasal swabs.
早期通过诊断检测发现严重急性呼吸综合征冠状病毒 2 感染，可促使采取措施减少传播并提高治疗效果，尤其是对免疫功能低下等弱势群体而言。最近的证据表明，对于抗原和分子新型冠状病毒病 2019 检测，在感染早期，同时采集鼻拭子和咽拭子样本可提高临床敏感性。我们敦促检测制造商验证与咽拭子联合使用的检测方法，同时也验证鼻拭子。
